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Bottle of Dermazen Calming Seborrheic Serum, 4 fl oz, with the text “Made by humans with moody skin” on the label.
Woman applying Dermazen Calming Seborrheic Serum to her scalp, with text “Safe for (curly, kinky, flat, and/or color treated) hair.”
Woman peacefully sleeping on white bed with text “Sleep your way to a clear scalp.”
Ingredient list for Calming Seborrheic Serum, including purified water, sea salt, colloidal silver, and essential oils.
Hand holding a bottle of Dermazen Calming Seborrheic Serum with text “Break the fungal biofilm, remove yeast naturally, stop the itching & flakes.”
Dermazen Calming Seborrheic Serum bottle with text: Steroid free, Toxin free, Prescription free, Worry free.
Woman with wet hair holding her head, text: “Amazing Results. My scalp is much happier (no more dandruff) and my thinning hair is noticeably fuller. - Dana H.”
Woman applying Dermazen Calming Seborrheic Serum to her scalp, text: “Dual Relief Formula: Targets the yeast causing your dandruff + Soothes your scalp right away.”
Hands holding and dispensing Dermazen Calming Seborrheic Serum, a drop falling into the palm.
Bottle of Dermazen Scalp Relief Serum on a light background with drops of the serum beside it.
Dermazen Calming Seborrheic Serum (8 fl oz) next to an open Cooling Rescue Roller (1 fl oz) on a white background.
Bottle of Dermazen Calming Seborrheic Serum, 8 fl oz, on a white background.
Calming Seborrheic Serum
  • Load image into Gallery viewer, Bottle of Dermazen Calming Seborrheic Serum, 4 fl oz, with the text “Made by humans with moody skin” on the label.
  • Load image into Gallery viewer, Woman applying Dermazen Calming Seborrheic Serum to her scalp, with text “Safe for (curly, kinky, flat, and/or color treated) hair.”
  • Load image into Gallery viewer, Woman peacefully sleeping on white bed with text “Sleep your way to a clear scalp.”
  • Load image into Gallery viewer, Ingredient list for Calming Seborrheic Serum, including purified water, sea salt, colloidal silver, and essential oils.
  • Load image into Gallery viewer, Hand holding a bottle of Dermazen Calming Seborrheic Serum with text “Break the fungal biofilm, remove yeast naturally, stop the itching & flakes.”
  • Load image into Gallery viewer, Dermazen Calming Seborrheic Serum bottle with text: Steroid free, Toxin free, Prescription free, Worry free.
  • Load image into Gallery viewer, Woman with wet hair holding her head, text: “Amazing Results. My scalp is much happier (no more dandruff) and my thinning hair is noticeably fuller. - Dana H.”
  • Load image into Gallery viewer, Woman applying Dermazen Calming Seborrheic Serum to her scalp, text: “Dual Relief Formula: Targets the yeast causing your dandruff + Soothes your scalp right away.”
  • Load image into Gallery viewer, Hands holding and dispensing Dermazen Calming Seborrheic Serum, a drop falling into the palm.
  • Load image into Gallery viewer, Bottle of Dermazen Scalp Relief Serum on a light background with drops of the serum beside it.
  • Load image into Gallery viewer, Dermazen Calming Seborrheic Serum (8 fl oz) next to an open Cooling Rescue Roller (1 fl oz) on a white background.
  • Load image into Gallery viewer, Bottle of Dermazen Calming Seborrheic Serum, 8 fl oz, on a white background.
  • Load image into Gallery viewer, Calming Seborrheic Serum

"This has been my holy grail. My scalp and face are calmer than they've been in years." - Samantha C., Repeat Customer

Calming Seborrheic Serum

4.5
Rated 4.5 out of 5 stars
1,599 Reviews

Soothe your scalp and face. This all-in-one serum helps disrupt the biofilm, clears away signs of fungus, and calms your skin naturally.

  1. Helps reduce and relieve signs of:
  2. Dandruff
  3. seborrheic dermatitis
  4. fungal conditions
  • Reduce flakes

  • Calm Redness

  • Soothe Itching

  • Safe for Malassezia

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FEATURED TESTIMONIAL
FEATURED TESTIMONIAL

Lecrae

/

Grammy Winner and Recording Artist

As a public figure with a moody scalp

this product has been a true game-changer for me. Dermazen has(See full testimonial)"

Malassezia-Safe \ Color-Safe \ 60-Day Guarantee \ Sulfate-Free \ Vegan \ Steriod-Free \ All-Natural \ Dermatologist Recommended \ Malassezia-Safe \ Color-Safe \ 60-Day Guarantee \ Sulfate-Free \ Vegan \ Steriod-Free \ All-Natural \ Dermatologist Recommended \

The #1 Dandruff & Seborrheic Dermatitis Mistake

Why Moisturizing Will Never Be Enough

From Moody Skin to Peace of Mind

Every photo represents a life changed forever. The next chapter of your healing story can start today. Get relief with Dermazen and put your flare-ups and frustration behind you.

Results like these aren’t guaranteed, but they are common.

Dermazen Calming Seborrheic Serum and Scalp Therapy Shampoo
A third-party clinical trial put Dermazen to the test — and the results speak for themselves.
92%
Flake-Free, Calm Scalp*

Over 92% of all participants in the study reported less dandruff, flakiness, and irritation.*

100%
Increase In Scalp Comfort*

Participants reported feeling more than twice as soothed and calm on their scalp after using Dermazen daily.*

Our 3-Step Process to Calm Your Skin

1. Disrupt the Biofilm

The fungus causing your moody skin is protected by a biofilm shield. Our unique formula safely disrupts this outer layer, exposing the fungus to Step #2.

2. Clear Away the Fungus

Once the biofilm is gone, you'll want to get rid of the fungus itself. We clear it out with a symphony of natural ingredients like tea tree, MSM (organic sulfur), sea salt, and more.

3. Soothe without Oils

The final step is to calm irritation and hydrate your skin without fungus-feeding oils. Aloe vera, niacinamide (vitamin B3), urea, and sodium hyaluronate (aka hyaluronic acid) bring the peace you're looking for.

Dermatologist Recommended

“I have been recommending the Calming Seborrheic Serum to people struggling with seborrheic dermatitis and psoriasis and they have seen significant improvement in their skin.”

- Dr. Maria Bonilla

What’s Inside

Aloe Leaf Juice

Helps soothe irritated scalp and signs of irritation

Xylitol

Works to naturally disrupt the biofilm layer and reduce signs of fungus

Grapefruit Seed Extract

Helps to calm moody scalps and support healthy hair and skin

Tea Tree Essential Oil

Helps calm and reduce signs of inflammation and fungus

Keeping it Zen

We practice ingredient minimalism. Our goal is to keep the list of ingredients humble while formulating products more effective than anything else. That’s why you won’t find parabens, sulfates, fragrances, or hard-to-pronounce chemicals. Those are the opposite of peaceful.

Zen Skin Trio

Zen Skin Trio

The foundation for malassezia skincare. The Zen Skin Trio is the perfect bundle to calm your scalp and face.

View Trio
Peaceful Skin System

Peaceful Skin System

The all-in-one system to soothe your flaky, red, and itchy face and scalp. Made by people with seborrheic dermatitis and recommended by dermatologists.

View System

How to Fix Your Flakes & Itching

I have textured hair.

I have straight/wavy hair.

  • 1

    Apply a generous amount of serum to your moody skin or scalp before bed, making sure to cover all of the affected area.

  • 2

    Massage in the formula as you thank your body for all its gifts.

  • 3

    In the morning*, rinse your hair with water or wash with a malassezia-safe shampoo before styling. If applied to the face, the soothing ingredients will absorb overnight.

  • 4

    Enjoy all-day peaceful skin and peace of mind.

*If you prefer to shower at night, just be sure to allow the serum to absorb into your scalp for at least two hours before rinsing or washing.

  • 1

    Apply the serum and massage it into your scalp and face thoroughly the night before (or at least two hours before) you plan to wash your hair - even if that is every week or two.

  • 2

    The serum can also be rinsed out with water (without shampoo) either with a full rinse or with a wet washcloth in between braids across the scalp.

  • 3

    Some folks with textured hair use the serum as a leave-in product, since the holistic ingredients will naturally absorb into the scalp for lasting relief.

4.5
Rated 4.5 out of 5 stars
Based on 1,599 reviews
Total 5 star reviews: 1.2k Total 4 star reviews: 193 Total 3 star reviews: 80 Total 2 star reviews: 40 Total 1 star reviews: 64
88%would recommend this product
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1,599 reviews
  • RH
    Rachel H.
    Verified Buyer
    I recommend this product
    Where did you need relief? Scalp
    What did this product help with? Flakes
    How old are you? Under 18
    What is your gender? Female
    What texture is your hair? Wavy
    Rated 5 out of 5 stars
    5 hours ago
    Excellent product!

    This serum has been amazing for my daughter. Wenceslao tried a lot of different solutions for flaky, itchy scalp and this has been the only one to help the most and give her relief.

    D Profile picture for Dermazen
    Dermazen
    20 seconds ago

    Aww yay, excellent product alert! 🌟 Thanks for sharing! We're here just ecstatic to hear that Dermazen's serum has been a game-changer for your daughter's flaky, itchy scalp 🤗. Sounds like you've tried a lot of different solutions, and we're happy we could bring her some much-needed relief 🙏. Thanks for trusting Dermazen - we're happy to have been a part of her journey!💚

  • AE
    Amber E.
    Verified Buyer
    I recommend this product
    Where did you need relief? Scalp
    What did this product help with? Flakes, Itching, Build-Up, Skin Health
    How old are you? 35-44
    What is your gender? Female
    What texture is your hair? Wavy
    Rated 5 out of 5 stars
    Yesterday
    Life saver

    This serum has been a Godsend. The other products in the line are great but this is the star player. Applying and massaging in are key, and then coupling the next day with the shampoo totally disrupts the cycle, dissolves patches and scaling, relieves the itchiness. If you're like me with extreme irritation, there will be an initial burning sensation but in the way you know its working deep! I also learned drying my hair is crucial afterwards to keep the growth and recurrence at bay in between serum applications.

    D Profile picture for Dermazen
    Dermazen
    Yesterday

    WOOHOO, life saver alert! Thanks for sharing your experience! We're blown away to hear that our serum's been a Godsend for you, and it's the star player in our line 🌟. Sounds like you've nailed the routine - applying + massaging in the serum, coupling it with the shampoo the next day to disrupt the cycle, dissolve patches + scaling, and relieve itchiness. We get it about that initial burning sensation with extreme irritation - that's like the serum doing its deep work 💪. And big ups for sharing that drying hair afterwards is crucial for keeping growth + recurrence at bay. Thanks for the detailed review and for trusting Dermazen!💚

  • ER
    Emily R.
    Verified Buyer
    I recommend this product
    Where did you need relief? Scalp
    What did this product help with? Itching, Build-Up, Skin Health
    How old are you? 35-44
    What is your gender? Female
    What texture is your hair? Wavy
    Rated 5 out of 5 stars
    2 days ago
    Excellent product

    I love this serum! I started using it and within the first week was sold on the results. It’s finally made significant progress toward ending pretty much constantly irritated scalp. Not irritating and I feel instant relief. Finally a product that works!

    D Profile picture for Dermazen
    Dermazen
    2 days ago

    We're super happy to hear that our Calming Seborrheic Serum worked wonders for you! Getting relief from that constant scalp irritation sounds like such a win. We're glad you noticed a big difference in just the first week; that's, honestly, awesome! And yay for a product that brings instant relief without any extra irritation. Thanks for loving our serum!💚😁 ✨

  • MW
    Mark W.
    Verified Buyer
    I recommend this product
    Where did you need relief? Face
    What did this product help with? Flakes, Skin Health
    How old are you? Over 65
    What is your gender? Male
    What texture is your hair? Straight
    Rated 5 out of 5 stars
    1 week ago
    Serum

    Actually helped dryness and flaking a lot. I had flaking to side and above my mouth that would crop up out of the blue. Started using your product and it doesn’t happen anymore.

    D Profile picture for Dermazen
    Dermazen
    1 week ago

    💚 Knowing that the Calming Seborrheic Serum has completely stopped that frustrating flaking around your mouth is absolutely incredible, Mark! We totally understand how unpredictable and annoying those sudden flare-ups can be, so the fact that you're not dealing with that anymore since starting the serum is just AMAZING. We're so glad! Your 5-star review and this fantastic clear skin success story is exactly why we created this product! Thank you for giving us a chance and for sharing this wonderful feedback! ✨🌱

  • HP
    Heather P.
    Verified Buyer
    I recommend this product
    Where did you need relief? Scalp
    What did this product help with? Flakes, Itching, Skin Health
    How old are you? 35-44
    What is your gender? Female
    What texture is your hair? Textured
    Rated 5 out of 5 stars
    2 weeks ago
    Clears up that hot inflammation feeling

    This cleared up my inflammation and calmed it almost immediately. This is a must have. It does end up having my shorter hair feel a little chalky so I would consider applying it at night and then washing hair in the morning considering I have 4C hair.

    D Profile picture for Dermazen
    Dermazen
    2 weeks ago

    Heather! This is exactly what we love to hear! 💚 Knowing that the Calming Seborrheic Serum cleared up your inflammation and gave you that immediate calming relief is incredible—there's nothing quite like getting rid of that uncomfortable hot inflammation feeling! We totally understand what you mean about the chalky texture with your 4C hair, and your nighttime application strategy sounds perfect! Applying it before bed and then washing in the morning is such a smart way to get all those amazing soothing benefits while working around the texture. The fact that you're calling it a "must have" and giving us those 5 stars has us absolutely thrilled! Your feedback about both the incredible results AND the practical application tips is so valuable! ✨💚

  • KJ
    Karen J.
    Verified Buyer
    I recommend this product
    Where did you need relief? Scalp, Face, Ears
    What did this product help with? Flakes, Itching
    How old are you? 35-44
    What is your gender? Female
    What texture is your hair? Textured
    Rated 4 out of 5 stars
    2 weeks ago
    Amazing Product

    This calming seborrheic serum is an all in one support for my seborrheic dermatitis - I use this on my scalp, and on anywhere where I have flare ups - and with consistent use my scalp has felt so different. Would 100% recommend this product.

    D Profile picture for Dermazen
    Dermazen
    2 weeks ago

    Love love love hearing that our Calming Seborrheic Serum is making such a difference for your seborrheic dermatitis, Karen! It's so great that you've found it works well on your scalp and other areas you have flare-ups. That versatility is exactly what we designed it for. Consistency really does make all the difference, and we're just happy you're feeling that improvement. Thanks for the amazing recommendation! 💚🤩

  • GC
    Gavin C.
    Verified Buyer
    I recommend this product
    What did this product help with? Flakes, Itching
    How old are you? 25-34
    What is your gender? Male
    What texture is your hair? Curly
    Rated 5 out of 5 stars
    2 weeks ago
    ONLY THING THAT WORKS

    I’ve dealt with itchy scalp for years and this is the ONLY product that works

    D Profile picture for Dermazen
    Dermazen
    1 week ago

    This review honestly made our day, Gavin - "ONLY THING THAT WORKS" are some seriously powerful words! 💚 We completely understand how frustrating it can be dealing with that persistent itchy scalp for years, trying product after product with no real relief. The fact that the Calming Seborrheic Serum is finally giving you the results you've been searching for is exactly why we created this formula! Your 5-star review and this incredible success story means EVERYTHING to us. Thank you for giving us a chance and for sharing this amazing feedback! ✨💚

  • R
    Regina
    I recommend this product
    Rated 5 out of 5 stars
    3 weeks ago
    5 Stars

    Love this