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Calming Seborrheic Serum
Woman applying Dermazen Calming Seborrheic Serum to her scalp, with text “Safe for (curly, kinky, flat, and/or color treated) hair.”
Woman peacefully sleeping on white bed with text “Sleep your way to a clear scalp.”
Ingredient list for Calming Seborrheic Serum, including purified water, sea salt, colloidal silver, and essential oils.
Hand holding a bottle of Dermazen Calming Seborrheic Serum with text “Break the fungal biofilm, remove yeast naturally, stop the itching & flakes.”
Dermazen Calming Seborrheic Serum bottle with text: Steroid free, Toxin free, Prescription free, Worry free.
Woman with wet hair holding her head, text: “Amazing Results. My scalp is much happier (no more dandruff) and my thinning hair is noticeably fuller. - Dana H.”
Woman applying Dermazen Calming Seborrheic Serum to her scalp, text: “Dual Relief Formula: Targets the yeast causing your dandruff + Soothes your scalp right away.”
Hands holding and dispensing Dermazen Calming Seborrheic Serum, a drop falling into the palm.
Bottle of Dermazen Scalp Relief Serum on a light background with drops of the serum beside it.
Calming Seborrheic Serum
Calming Seborrheic Serum
  • Load image into Gallery viewer, Calming Seborrheic Serum
  • Load image into Gallery viewer, Woman applying Dermazen Calming Seborrheic Serum to her scalp, with text “Safe for (curly, kinky, flat, and/or color treated) hair.”
  • Load image into Gallery viewer, Woman peacefully sleeping on white bed with text “Sleep your way to a clear scalp.”
  • Load image into Gallery viewer, Ingredient list for Calming Seborrheic Serum, including purified water, sea salt, colloidal silver, and essential oils.
  • Load image into Gallery viewer, Hand holding a bottle of Dermazen Calming Seborrheic Serum with text “Break the fungal biofilm, remove yeast naturally, stop the itching & flakes.”
  • Load image into Gallery viewer, Dermazen Calming Seborrheic Serum bottle with text: Steroid free, Toxin free, Prescription free, Worry free.
  • Load image into Gallery viewer, Woman with wet hair holding her head, text: “Amazing Results. My scalp is much happier (no more dandruff) and my thinning hair is noticeably fuller. - Dana H.”
  • Load image into Gallery viewer, Woman applying Dermazen Calming Seborrheic Serum to her scalp, text: “Dual Relief Formula: Targets the yeast causing your dandruff + Soothes your scalp right away.”
  • Load image into Gallery viewer, Hands holding and dispensing Dermazen Calming Seborrheic Serum, a drop falling into the palm.
  • Load image into Gallery viewer, Bottle of Dermazen Scalp Relief Serum on a light background with drops of the serum beside it.
  • Load image into Gallery viewer, Calming Seborrheic Serum
  • Load image into Gallery viewer, Calming Seborrheic Serum

"This has been my holy grail. My scalp and face are calmer than they've been in years." - Samantha C., Repeat Customer

Calming Seborrheic Serum

4.5
Rated 4.5 out of 5 stars
1,607 Reviews

Soothe your scalp and face. This all-in-one serum helps disrupt the biofilm, clears away signs of fungus, and calms your skin naturally.

  1. Helps reduce and relieve signs of:
  2. Dandruff
  3. seborrheic dermatitis
  4. fungal conditions
  • Reduce flakes

  • Calm Redness

  • Soothe Itching

  • Safe for Malassezia

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FEATURED TESTIMONIAL
FEATURED TESTIMONIAL

Lecrae

/

Grammy Winner and Recording Artist

As a public figure with a moody scalp

this product has been a true game-changer for me. Dermazen has(See full testimonial)"

Malassezia-Safe \ Color-Safe \ 60-Day Guarantee \ Sulfate-Free \ Vegan \ Steriod-Free \ All-Natural \ Dermatologist Recommended \ Malassezia-Safe \ Color-Safe \ 60-Day Guarantee \ Sulfate-Free \ Vegan \ Steriod-Free \ All-Natural \ Dermatologist Recommended \

The #1 Dandruff & Seborrheic Dermatitis Mistake

Why Moisturizing Will Never Be Enough

From Moody Skin to Peace of Mind

Every photo represents a life changed forever. The next chapter of your healing story can start today. Get relief with Dermazen and put your flare-ups and frustration behind you.

Results like these aren’t guaranteed, but they are common.

Dermazen Calming Seborrheic Serum and Scalp Therapy Shampoo
A third-party clinical trial put Dermazen to the test — and the results speak for themselves.
92%
Flake-Free, Calm Scalp*

Over 92% of all participants in the study reported less dandruff, flakiness, and irritation.*

100%
Increase In Scalp Comfort*

Participants reported feeling more than twice as soothed and calm on their scalp after using Dermazen daily.*

Our 3-Step Process to Calm Your Skin

1. Disrupt the Biofilm

The fungus causing your moody skin is protected by a biofilm shield. Our unique formula safely disrupts this outer layer, exposing the fungus to Step #2.

2. Clear Away the Fungus

Once the biofilm is gone, you'll want to get rid of the fungus itself. We clear it out with a symphony of natural ingredients like tea tree, MSM (organic sulfur), sea salt, and more.

3. Soothe without Oils

The final step is to calm irritation and hydrate your skin without fungus-feeding oils. Aloe vera, niacinamide (vitamin B3), urea, and sodium hyaluronate (aka hyaluronic acid) bring the peace you're looking for.

Dermatologist Recommended

“I have been recommending the Calming Seborrheic Serum to people struggling with seborrheic dermatitis and psoriasis and they have seen significant improvement in their skin.”

- Dr. Maria Bonilla

What’s Inside

Aloe Leaf Juice

Helps soothe irritated scalp and signs of irritation

Xylitol

Works to naturally disrupt the biofilm layer and reduce signs of fungus

Grapefruit Seed Extract

Helps to calm moody scalps and support healthy hair and skin

Tea Tree Essential Oil

Helps calm and reduce signs of inflammation and fungus

Keeping it Zen

We practice ingredient minimalism. Our goal is to keep the list of ingredients humble while formulating products more effective than anything else. That’s why you won’t find parabens, sulfates, fragrances, or hard-to-pronounce chemicals. Those are the opposite of peaceful.

Zen Skin Trio

Zen Skin Trio

The foundation for malassezia skincare. The Zen Skin Trio is the perfect bundle to calm your scalp and face.

View Trio
Peaceful Skin System

Peaceful Skin System

The all-in-one system to soothe your flaky, red, and itchy face and scalp. Made by people with seborrheic dermatitis and recommended by dermatologists.

View System

How to Fix Your Flakes & Itching

I have textured hair.

I have straight/wavy hair.

  • 1

    Apply a generous amount of serum to your moody skin or scalp before bed, making sure to cover all of the affected area.

  • 2

    Massage in the formula as you thank your body for all its gifts.

  • 3

    In the morning*, rinse your hair with water or wash with a malassezia-safe shampoo before styling. If applied to the face, the soothing ingredients will absorb overnight.

  • 4

    Enjoy all-day peaceful skin and peace of mind.

*If you prefer to shower at night, just be sure to allow the serum to absorb into your scalp for at least two hours before rinsing or washing.

  • 1

    Apply the serum and massage it into your scalp and face thoroughly the night before (or at least two hours before) you plan to wash your hair - even if that is every week or two.

  • 2

    The serum can also be rinsed out with water (without shampoo) either with a full rinse or with a wet washcloth in between braids across the scalp.

  • 3

    Some folks with textured hair use the serum as a leave-in product, since the holistic ingredients will naturally absorb into the scalp for lasting relief.

4.5
Rated 4.5 out of 5 stars
Based on 1,607 reviews
Total 5 star reviews: 1.2k Total 4 star reviews: 194 Total 3 star reviews: 80 Total 2 star reviews: 39 Total 1 star reviews: 64
89%would recommend this product
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1,607 reviews
  • MV
    Melissa V.
    Verified Buyer
    I recommend this product
    Where did you need relief? Face
    What did this product help with? Itching, Skin Tone, Flakes
    How old are you? Under 18
    What is your gender? Female
    What texture is your hair? Wavy
    Rated 5 out of 5 stars
    4 days ago
    Amazing!

    Just after using this for a week, my daughter's skin cleared up! I'm so thankful I found this product.

    D Profile picture for Dermazen
    Dermazen
    4 days ago

    Melissa, a whole week and already clear skin? That's absolutely incredible! 🤩 As a parent, there's nothing quite like that feeling of relief when you find something that actually works for your child's skin. We're so thrilled that our Calming Seborrheic Serum delivered such fast results for your daughter!

    It's moments like these that remind us why we do what we do - helping families find real solutions that make a genuine difference. Your daughter's skin is going to love the continued care, and we're just so grateful you gave Dermazen a chance to help. Thank you for this amazing 5-star review and for trusting us with your daughter's skincare needs!💚🙌

  • TR
    Teodora R.
    Verified Buyer
    I recommend this product
    Where did you need relief? Scalp
    What did this product help with? Itching
    How old are you? 35-44
    What is your gender? Female
    What texture is your hair? Wavy
    Rated 5 out of 5 stars
    4 days ago
    Great product.

    This serum is amazing. It helped with my itching scalp.

    Will order the shampoo too.

    D Profile picture for Dermazen
    Dermazen
    4 days ago

    Oh wow, that's fantastic! 🤩 It sounds like our Calming Seborrheic Serum has really come to the rescue for your scalp, and we couldn't be more thrilled. Here’s to saying goodbye to that pesky itch, and a warm welcome to our shampoo! We can't wait for you to experience the full Dermazen effect. Thanks for giving our serum a try and sharing your experience. 💚😁

  • JP
    Joelle P.
    Verified Buyer
    I recommend this product
    Where did you need relief? Face, Ears, Scalp
    What did this product help with? Skin Health, Itching, Build-Up, Flakes
    How old are you? 25-34
    What is your gender? Female
    What texture is your hair? Straight
    Rated 4 out of 5 stars
    5 days ago
    Serum

    Very helpful step, I primarily use for my face but starting to add to my hair care routine now that I’ve finished using my prescription hair serum (let’s see how the difference is). I do feel like it helps in my skin care before adding the Dermazen moisturizer. Can also burn temporarily when I have big flare ups/cracked skin. The nozzle is really good for using it in my hair but wish there was a pump or spray top that I cane with it so I can change between options when I’m using it for my scalp versus my face

    D Profile picture for Dermazen
    Dermazen
    5 days ago

    Love hearing that our Calming Seborrheic Serum is working so well for you, Joelle! It's great that you're finding it helpful for both your face and that you're expanding into using it for your hair care routine—that versatility is exactly what we designed it for. We totally understand about the temporary burning sensation during flare-ups, and it sounds like you've found a great routine pairing it with our moisturizer! Really appreciate the feedback about the nozzle and your suggestion for different applicator options—that's super helpful for us to know about. Thanks for the 4 stars and for giving Dermazen a try! 💚🤩

  • QT
    Quinesha T.
    Verified Buyer
    I recommend this product
    Where did you need relief? Scalp
    What did this product help with? Itching, Build-Up, Flakes
    How old are you? Under 18
    What is your gender? Female
    What texture is your hair? Textured
    Rated 5 out of 5 stars
    6 days ago
    Really works

    This really works! Expensive but works. Why not try it, you’ve tried everything else!

    D Profile picture for Dermazen
    Dermazen
    5 days ago

    Quinesha, your review perfectly captures what so many of our customers experience, that moment when you finally find something that actually works after trying everything else. We know the investment can feel significant, but we're so glad you took the leap and that it's paying off with real results!

    Your "why not try it" attitude is exactly what we love to see, and we're confident that others who have been on that same frustrating journey will find hope in your experience. Thank you for this fantastic 5-star review and for trusting Dermazen to deliver the relief you were looking for! 💚

  • TG
    Toriahn G.
    Verified Buyer
    I recommend this product
    Where did you need relief? Scalp
    What did this product help with? Flakes, Itching, Build-Up
    How old are you? 18-24
    What is your gender? Prefer not to say
    What texture is your hair? Curly
    Rated 5 out of 5 stars
    6 days ago
    Calming Seborrheic Serum

    This product is so good!!! I have 4b hair and I’ve had seb derm since 2019- 2020 ish. Up until recently I found this product and this is the only thing that has given my scalp relief. I would say for the best results you need to leave this stuff on your scalp before you shampoo for a minimum of 4 hours but overnight for max results!!! At first I thought this product wasn’t working but I wasn’t leaving it on my scalp long enough. My scalp can last a few weeks without a wash, no flakes, and itchiness when I use this!

    D Profile picture for Dermazen
    Dermazen
    6 days ago

    This review! 🙌 We're absolutely delighted to hear that our Calming Seborrheic Serum has been a game-changer for your scalp, Toriahn! We know how frustrating and stubborn seborrheic dermatitis can be, so it's wonderful to hear that the serum is providing you with much-needed relief. You also make a fantastic point about using the serum for an extended period of time. For best results, letting the serum really soak in and work its magic overnight can make a huge difference.

    Lastly, we want to thank you for sharing your journey with us. Your review not only provides helpful information for others struggling with seb derm, but it also reinforces our commitment to developing products that make a real, meaningful impact. 💚

  • LJ
    Lauren J.
    Verified Buyer
    I recommend this product
    Where did you need relief? Scalp, Face, Ears
    What did this product help with? Itching, Build-Up, Skin Tone, Skin Health, Flakes
    How old are you? 25-34
    What is your gender? Female
    What texture is your hair? Curly
    Rated 5 out of 5 stars
    1 week ago
    Amazing Product!

    Haven’t felt the relief this product gives me in decades! Has helped me with buildup, redness, and itching. Highly recommend and worth every penny!

    D Profile picture for Dermazen
    Dermazen
    1 week ago

    Thank you for this incredible 5-star review! Decades of searching for relief and finally finding it with our Calming Seborrheic Serum, what an incredible breakthrough, Lauren! It's wonderful that you're experiencing such significant improvement with the buildup, redness, and itching. That comprehensive relief you're describing is exactly what makes this serum so special for managing seborrheic concerns. There's nothing more rewarding than knowing we've helped you achieve the comfort and peace you've been seeking for so long!💚

  • SB
    Shaun B.
    Verified Buyer
    I recommend this product
    Where did you need relief? Scalp, Face
    What did this product help with? Flakes, Build-Up
    How old are you? Over 65
    What is your gender? Male
    What texture is your hair? Other
    Rated 5 out of 5 stars
    1 week ago
    Flakes no more.

    it is great.

    D Profile picture for Dermazen
    Dermazen
    1 week ago

    Shaun, this is exactly what we love to hear! "Flakes no more" - those three words say it all! It sounds like the Calming Seborrheic Serum has delivered exactly what you needed, giving you that clean, comfortable scalp without those pesky flakes. There's nothing quite like finding a product that tackles the issue head-on and gives you that confidence back. Your experience perfectly captures what makes this serum so effective for seborrheic concerns! Thanks for this incredible 5-star review and for trusting Dermazen with your scalp care! 💚

  • AC
    Allison C.
    Verified Buyer
    I recommend this product
    Where did you need relief? Scalp, Face
    What did this product help with? Skin Health
    How old are you? 35-44
    What is your gender? Female
    What texture is your hair? Straight
    Rated 5 out of 5 stars
    1 week ago
    Works on scalp and face.

    Effective product. My skin and scalp are more balanced after use.

    D Profile picture for Dermazen
    Dermazen
    1 week ago

    The Calming Seborrheic Serum seems to be working its magic on both your scalp and face - that's the kind of versatility that makes a product truly special! It's wonderful that you're experiencing that balanced, comfortable feeling across different areas. Your experience highlights how effective this serum can be for managing seborrheic issues wherever they pop up. Thanks for this incredible 5-star review and for trusting Dermazen with your skincare! 💚