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Bottle of Dermazen Calming Seborrheic Serum, 4 fl oz, with the text “Made by humans with moody skin” on the label.
Woman applying Dermazen Calming Seborrheic Serum to her scalp, with text “Safe for (curly, kinky, flat, and/or color treated) hair.”
Woman peacefully sleeping on white bed with text “Sleep your way to a clear scalp.”
Ingredient list for Calming Seborrheic Serum, including purified water, sea salt, colloidal silver, and essential oils.
Hand holding a bottle of Dermazen Calming Seborrheic Serum with text “Break the fungal biofilm, remove yeast naturally, stop the itching & flakes.”
Dermazen Calming Seborrheic Serum bottle with text: Steroid free, Toxin free, Prescription free, Worry free.
Woman with wet hair holding her head, text: “Amazing Results. My scalp is much happier (no more dandruff) and my thinning hair is noticeably fuller. - Dana H.”
Woman applying Dermazen Calming Seborrheic Serum to her scalp, text: “Dual Relief Formula: Targets the yeast causing your dandruff + Soothes your scalp right away.”
Hands holding and dispensing Dermazen Calming Seborrheic Serum, a drop falling into the palm.
Bottle of Dermazen Scalp Relief Serum on a light background with drops of the serum beside it.
Dermazen Calming Seborrheic Serum (8 fl oz) next to an open Cooling Rescue Roller (1 fl oz) on a white background.
Bottle of Dermazen Calming Seborrheic Serum, 8 fl oz, on a white background.
Calming Seborrheic Serum
  • Load image into Gallery viewer, Bottle of Dermazen Calming Seborrheic Serum, 4 fl oz, with the text “Made by humans with moody skin” on the label.
  • Load image into Gallery viewer, Woman applying Dermazen Calming Seborrheic Serum to her scalp, with text “Safe for (curly, kinky, flat, and/or color treated) hair.”
  • Load image into Gallery viewer, Woman peacefully sleeping on white bed with text “Sleep your way to a clear scalp.”
  • Load image into Gallery viewer, Ingredient list for Calming Seborrheic Serum, including purified water, sea salt, colloidal silver, and essential oils.
  • Load image into Gallery viewer, Hand holding a bottle of Dermazen Calming Seborrheic Serum with text “Break the fungal biofilm, remove yeast naturally, stop the itching & flakes.”
  • Load image into Gallery viewer, Dermazen Calming Seborrheic Serum bottle with text: Steroid free, Toxin free, Prescription free, Worry free.
  • Load image into Gallery viewer, Woman with wet hair holding her head, text: “Amazing Results. My scalp is much happier (no more dandruff) and my thinning hair is noticeably fuller. - Dana H.”
  • Load image into Gallery viewer, Woman applying Dermazen Calming Seborrheic Serum to her scalp, text: “Dual Relief Formula: Targets the yeast causing your dandruff + Soothes your scalp right away.”
  • Load image into Gallery viewer, Hands holding and dispensing Dermazen Calming Seborrheic Serum, a drop falling into the palm.
  • Load image into Gallery viewer, Bottle of Dermazen Scalp Relief Serum on a light background with drops of the serum beside it.
  • Load image into Gallery viewer, Dermazen Calming Seborrheic Serum (8 fl oz) next to an open Cooling Rescue Roller (1 fl oz) on a white background.
  • Load image into Gallery viewer, Bottle of Dermazen Calming Seborrheic Serum, 8 fl oz, on a white background.
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"This has been my holy grail. My scalp and face are calmer than they've been in years." - Samantha C., Repeat Customer

Calming Seborrheic Serum

4.6
Rated 4.6 out of 5 stars
1,431 Reviews

Soothe your scalp and face. This all-in-one serum disrupts the biofilm, clears away fungus, and calms your skin naturally.

  1. Helps with:
  2. Dandruff
  3. seborrheic dermatitis
  4. fungal conditions
  • Reduce flakes

  • Calm Redness

  • Soothe Itching

  • Safe for Malassezia

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Malassezia-Safe \ Color-Safe \ 60-Day Guarantee \ Sulfate-Free \ Vegan \ Steriod-Free \ All-Natural \ Dermatologist Recommended \ Malassezia-Safe \ Color-Safe \ 60-Day Guarantee \ Sulfate-Free \ Vegan \ Steriod-Free \ All-Natural \ Dermatologist Recommended \

The #1 Dandruff & Seborrheic Dermatitis Mistake

Why Moisturizing Will Never Be Enough

From Moody Skin to Peace of Mind

Every photo represents a life changed forever. The next chapter of your healing story can start today. Get relief with Dermazen and put your flare-ups and frustration behind you.

Results like these aren’t guaranteed, but they are common.

Our 3-Step Process to Calm Your Skin

1. Disrupt the Biofilm

The fungus causing your moody skin is protected by a biofilm shield. Our unique formula safely disrupts this outer layer, exposing the fungus to Step #2.

2. Clear Away the Fungus

Once the biofilm is gone, you’ll want to get rid of the fungus itself. We clear it out with a symphony of natural ingredients like grapefruit seed extract, tea tree, organic sulfur, sea salt, and more.

3. Soothe without Oils

The final step is to calm irritation and hydrate your skin without fungus-feeding oils. Aloe vera, vitamin B3, urea, and hyaluronic acid bring the peace you’re looking for.

Why your dandruff shampoo has failed you

If your dandruff shampoo doesn’t target the biofilm protecting the fungus, it can never solve the root cause of your flakes and itching.

Plus, if your shampoo contains oils, then it’s feeding the fungus each time you shower.

Dermatologist Recommended

“I have been recommending the Calming Seborrheic Serum to my patients with seborrheic dermatitis and psoriasis and they have seen significant improvement in their skin.”

- Dr. Maria Bonilla

What’s Inside

200x Concentrated Aloe

Soothe your irritated scalp and calm inflamed skin

Xylitol

Naturally disrupt the biofilm layer to weaken the fungus

Grapefruit Seed Extract

Eliminate fungus and boost antioxidants

Tea Tree Essential Oil

Calm inflammation and eliminate fungus

Keeping it Zen

We practice ingredient minimalism. Our goal is to keep the list of ingredients humble while formulating products more effective than anything else. That’s why you won’t find parabens, sulfates, fragrances, or hard-to-pronounce chemicals. Those are the opposite of peaceful.

Zen Skin Trio

Zen Skin Trio

The the foundation for malassezia skincare. The Zen Skin Trio is the perfect bundle to calm your scalp and face.

View Trio
Peaceful Skin System

Peaceful Skin System

The all-in-one system to soothe your flaky, red, and itchy face and scalp. Made by people with seborrheic dermatitis and recommended by dermatologists.

View System

How to Fix Your Flakes & Itching

I have textured hair.

I have straight/wavy hair.

  • 1

    Apply a generous amount of serum to your moody skin or scalp before bed, making sure to cover all of the affected area.

  • 2

    Massage in the formula as you thank your body for all its gifts.

  • 3

    In the morning*, rinse your hair with water or wash with a malassezia-safe shampoo before styling. If applied to the face, the soothing ingredients will absorb overnight.

  • 4

    Enjoy all-day peaceful skin and peace of mind.

*If you prefer to shower at night, just be sure to allow the serum to absorb into your scalp for at least two hours before rinsing or washing.

  • 1

    Apply the serum and massage it into your scalp and face thoroughly the night before (or at least two hours before) you plan to wash your hair - even if that is every week or two.

  • 2

    The serum can also be rinsed out with water (without shampoo) either with a full rinse or with a wet washcloth in between braids across the scalp.

  • 3

    Some folks with textured hair use the serum as a leave-in product, since the holistic ingredients will naturally absorb into the scalp for lasting relief.

4.6
Rated 4.6 out of 5 stars
Based on 1,431 reviews
Total 5 star reviews: 1.1k Total 4 star reviews: 184 Total 3 star reviews: 68 Total 2 star reviews: 33 Total 1 star reviews: 56
89%would recommend these products
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1,431 reviews
  • MS
    Malcolm S.
    Verified Buyer
    Calming Seborrheic Serum
    Reviewing
    Calming Seborrheic Serum
    I recommend this product
    Where did you need relief? Face, Scalp
    What did this product help with? Flakes, Itching, Build-Up, Skin Tone, Skin Health
    How old are you? 25-34
    What is your gender? Male
    What texture is your hair? Wavy
    Rated 5 out of 5 stars
    6 hours ago
    IT WORKS !!!

    I will admit I was initially skeptical, but this products works as promised! I’ve dealt with seborrheic dermatitis for years and I’ve tried many prescription creams, shampoos, and topical solutions that did not work. It’s been about three weeks and I’d say it’s eliminated about 85% of my issues. I will be repurchasing for maintenance purposes.

  • T Profile picture for Tressa
    Tressa
    Calming Seborrheic Serum
    Reviewing
    Calming Seborrheic Serum
    I recommend this product
    Where did you need relief? Scalp, Ears
    What did this product help with? Flakes, Itching, Build-Up
    How old are you? 45-54
    What is your gender? Female
    What texture is your hair? Textured
    Rated 5 out of 5 stars
    2 days ago
    The only product that works!

    I've been using the serum and moisturizer for 3 months now.

    Since I'm African American , I only shampoo my hair one a week, or sometimes 2-3 weeks if I'm wearing braids. (Use dry shampoo sometimes which is drying)

    I noticed a difference in the itching calming down after the first use. I'm also able to wear my braided styles longer and don't have dandruff caught in the base of the braids which was so embarrassing.

    D Profile picture for Dermazen
    Dermazen
    Yesterday

    We're overjoyed to read your phenomenal review, Tressa! We understand how challenging those issues can be, especially with protective styles, so we're honored our products have become a trusted solution. Thank you for being a part of our community and for your continued support. We're so grateful to be on this journey with you!💚

  • ES
    Erin S.
    Verified Buyer
    Calming Seborrheic Serum
    Reviewing
    Calming Seborrheic Serum
    I recommend this product
    Where did you need relief? Scalp
    What did this product help with? Flakes, Itching, Build-Up
    How old are you? 25-34
    What is your gender? Female
    What texture is your hair? Straight
    Rated 5 out of 5 stars
    3 days ago
    My itch is gone

    I have struggled with it itchy, flaky scalp for as long as I can remember, especially during the winter months, and I have tried about every dandruff shampoo out there. This itch relief serum works amazingly and I am definitely re-ordering. Also going to be ordering the shampoo and conditioner to go along with it.

    D Profile picture for Dermazen
    Dermazen
    Yesterday

    Erin, we are thrilled knowing that you have found SO much relief using our products! We do our best to bring the best quality products to our customers. With that being said, we're so excited to have you apart of our community and we appreciate your positive review 💚

  • SW
    Sondria W.
    Verified Buyer
    Calming Seborrheic Serum
    Reviewing
    Calming Seborrheic Serum
    I recommend this product
    Where did you need relief? Scalp, Face
    What did this product help with? Build-Up, Flakes, Skin Health
    How old are you? 25-34
    What is your gender? Female
    What texture is your hair? Curly
    Rated 5 out of 5 stars
    6 days ago
    Amazing

    Product does Exactly what it’s suppose to do and I absolutely love that I can use it on my face and scalp! My hair has grown so much since I’ve began using this.

    D Profile picture for Dermazen
    Dermazen
    Yesterday

    Thank you so much, Sondria! We are over the moon hearing that your hair has grown so much since using our products and that you have finally found relief. Thank you for your incredible review and sharing this feedback with us 💚

  • MT
    Martha T.
    Verified Buyer
    Calming Seborrheic Serum
    Reviewing
    Calming Seborrheic Serum
    I do not recommend this product
    Where did you need relief? Scalp, Ears
    How old are you? 35-44
    What is your gender? Female
    What texture is your hair? Straight
    Rated 1 out of 5 stars
    1 week ago
    Intrigued by the ingredients, but no improvements after 4wks

    For 4 weeks, ive applied the serum 1-2x a day allowing it to soak for 2-12hrs. I’ve been using thedermazen shampoo every day or every other day along with a 3% salicylic acid shampoo. The shampoo doesn’t burn. But the serum definitely burns my scalp. Scalp is pretty irritated. I haven’t noticed any improvement in my scalp. I’ve had a severe patch since a failed pregnancy 2yrs ago (a living baby 1yr ago). So, plenty of hormone changes and stress. And I have oily skin. My dermatologist is ready to propose a systemic antifungal management 😫 I really wanted this to work! I have a background in wound care nursing and silver is amazing for biofilms and antifungal/antibacterical properties. But, I think using an anti fungal powder as my “dry shampoo” was helping more than this. 😔

    D Profile picture for Dermazen
    Dermazen
    Yesterday

    I'm truly sorry to hear that our products didn't provide the relief you were hoping for, Martha. It's incredibly frustrating when you've been dealing with a scalp condition for so long, especially after major life events like you've experienced. With that being said, thank you for sharing your review, and we'd love to see how we can help you!

    While our serum is designed to be gentle, every individual can react differently. We want to make this right, so please email us at support@dermazen.co 💚

  • CF
    Chase F.
    Verified Buyer
    Calming Seborrheic Serum
    Reviewing
    Calming Seborrheic Serum
    I recommend this product
    Where did you need relief? Scalp, Face, Ears
    What did this product help with? Flakes, Itching
    How old are you? 25-34
    What is your gender? Male
    What texture is your hair? Wavy
    Rated 5 out of 5 stars
    1 week ago
    Helps control

    I have had dandruff for about 15 years and have had varying levels of success in controlling it. The last treatment option I had gotten was a topical steroid and a medicated shampoo which did control my dandruff for a while but the shampoo completely stopped working and I’ve been looking for less medicated ways to deal with my dandruff. I unfortunately can’t say that this product has gotten rid of my dandruff, but it helps deal with a lot of the itching. I’m looking forward to trying Dermazen’s shampoo. My ears also suffer a bit from flaky skin, and I’ve put this on a qtip and applied it there and it definitely helps that as well

    D Profile picture for Dermazen
    Dermazen
    Yesterday

    Chase, thank you for this review! We completely understand that the serum hasn't completely removed the dandruff, but you may find that pairing the Dandruff Shampoo will help solve that for you! Our Calming Serum is wonderful for helping break down the biofilm, but our shampoo is more geared towards dandruff 💚

    If you need any further support, don't hesitate to reach out to our team at support@dermazen.co and we're happy to help!

  • AW
    Adam W.
    Verified Buyer
    Calming Seborrheic Serum
    Reviewing
    Calming Seborrheic Serum
    I recommend this product
    Where did you need relief? Scalp
    What did this product help with? Itching, Flakes
    How old are you? 25-34
    What is your gender? Male
    What texture is your hair? Textured
    Rated 4 out of 5 stars
    1 week ago
    Solid

    Works good, for me does not work without the shampoo

    D Profile picture for Dermazen
    Dermazen
    Yesterday

    Thank you for your honest review, Adam! We're glad to hear the product is working well for you when used with our shampoo. Every scalp and hair type is unique, so we appreciate you taking the time to share your experience and routine.

    Finding the right combination of products can take some trial and error, but sticking with a complete regimen often yields the best results. If you ever have any questions or need recommendations on how to maximize the benefits, feel free to reach out to our team at support@dermazen.co. Thanks for being part of our community!🙏

  • DL
    DANIEL L.
    Verified Buyer
    Calming Seborrheic Serum
    Reviewing
    Calming Seborrheic Serum
    I recommend this product
    Where did you need relief? Scalp
    What did this product help with? Flakes, Itching, Skin Health
    How old are you? 35-44
    What is your gender? Male
    What texture is your hair? Wavy
    Rated 5 out of 5 stars
    1 week ago
    It really works!

    I have tried so many products and spent a lot of money and I am so happy I found this product through my wife seeing it on Instagram! I love the ease of use, quality ingredients and the way my scalp has improved. I no longer have pain and itchiness, redness and spots that have been there for years causing problems are gone! I really can’t believe it and absolutely recommend it to others.

    D Profile picture for Dermazen
    Dermazen
    Yesterday

    Daniel, we are beyond thrilled to read your review! It's incredible to hear that our products have provided you with so much relief after trying so many other products. We're honored that your wife introduced you to our brand, and that you've experienced such fantastic results. Thank you for your review, and we're so grateful to be on this journey with you!💚

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