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Bottle of Dermazen Calming Seborrheic Serum, 4 fl oz, with the text “Made by humans with moody skin” on the label.
Woman applying Dermazen Calming Seborrheic Serum to her scalp, with text “Safe for (curly, kinky, flat, and/or color treated) hair.”
Woman peacefully sleeping on white bed with text “Sleep your way to a clear scalp.”
Ingredient list for Calming Seborrheic Serum, including purified water, sea salt, colloidal silver, and essential oils.
Hand holding a bottle of Dermazen Calming Seborrheic Serum with text “Break the fungal biofilm, remove yeast naturally, stop the itching & flakes.”
Dermazen Calming Seborrheic Serum bottle with text: Steroid free, Toxin free, Prescription free, Worry free.
Woman with wet hair holding her head, text: “Amazing Results. My scalp is much happier (no more dandruff) and my thinning hair is noticeably fuller. - Dana H.”
Woman applying Dermazen Calming Seborrheic Serum to her scalp, text: “Dual Relief Formula: Targets the yeast causing your dandruff + Soothes your scalp right away.”
Hands holding and dispensing Dermazen Calming Seborrheic Serum, a drop falling into the palm.
Bottle of Dermazen Scalp Relief Serum on a light background with drops of the serum beside it.
Dermazen Calming Seborrheic Serum (8 fl oz) next to an open Cooling Rescue Roller (1 fl oz) on a white background.
Bottle of Dermazen Calming Seborrheic Serum, 8 fl oz, on a white background.
Calming Seborrheic Serum
  • Load image into Gallery viewer, Bottle of Dermazen Calming Seborrheic Serum, 4 fl oz, with the text “Made by humans with moody skin” on the label.
  • Load image into Gallery viewer, Woman applying Dermazen Calming Seborrheic Serum to her scalp, with text “Safe for (curly, kinky, flat, and/or color treated) hair.”
  • Load image into Gallery viewer, Woman peacefully sleeping on white bed with text “Sleep your way to a clear scalp.”
  • Load image into Gallery viewer, Ingredient list for Calming Seborrheic Serum, including purified water, sea salt, colloidal silver, and essential oils.
  • Load image into Gallery viewer, Hand holding a bottle of Dermazen Calming Seborrheic Serum with text “Break the fungal biofilm, remove yeast naturally, stop the itching & flakes.”
  • Load image into Gallery viewer, Dermazen Calming Seborrheic Serum bottle with text: Steroid free, Toxin free, Prescription free, Worry free.
  • Load image into Gallery viewer, Woman with wet hair holding her head, text: “Amazing Results. My scalp is much happier (no more dandruff) and my thinning hair is noticeably fuller. - Dana H.”
  • Load image into Gallery viewer, Woman applying Dermazen Calming Seborrheic Serum to her scalp, text: “Dual Relief Formula: Targets the yeast causing your dandruff + Soothes your scalp right away.”
  • Load image into Gallery viewer, Hands holding and dispensing Dermazen Calming Seborrheic Serum, a drop falling into the palm.
  • Load image into Gallery viewer, Bottle of Dermazen Scalp Relief Serum on a light background with drops of the serum beside it.
  • Load image into Gallery viewer, Dermazen Calming Seborrheic Serum (8 fl oz) next to an open Cooling Rescue Roller (1 fl oz) on a white background.
  • Load image into Gallery viewer, Bottle of Dermazen Calming Seborrheic Serum, 8 fl oz, on a white background.
  • Load image into Gallery viewer, Calming Seborrheic Serum

"This has been my holy grail. My scalp and face are calmer than they've been in years." - Samantha C., Repeat Customer

Calming Seborrheic Serum

4.5
Rated 4.5 out of 5 stars
1,592 Reviews

Soothe your scalp and face. This all-in-one serum helps disrupt the biofilm, clears away signs of fungus, and calms your skin naturally.

  1. Helps reduce and relieve signs of:
  2. Dandruff
  3. seborrheic dermatitis
  4. fungal conditions
  • Reduce flakes

  • Calm Redness

  • Soothe Itching

  • Safe for Malassezia

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FEATURED TESTIMONIAL
FEATURED TESTIMONIAL

Lecrae

/

Grammy Winner and Recording Artist

As a public figure with a moody scalp

this product has been a true game-changer for me. Dermazen has(See full testimonial)"

Malassezia-Safe \ Color-Safe \ 60-Day Guarantee \ Sulfate-Free \ Vegan \ Steriod-Free \ All-Natural \ Dermatologist Recommended \ Malassezia-Safe \ Color-Safe \ 60-Day Guarantee \ Sulfate-Free \ Vegan \ Steriod-Free \ All-Natural \ Dermatologist Recommended \

The #1 Dandruff & Seborrheic Dermatitis Mistake

Why Moisturizing Will Never Be Enough

From Moody Skin to Peace of Mind

Every photo represents a life changed forever. The next chapter of your healing story can start today. Get relief with Dermazen and put your flare-ups and frustration behind you.

Results like these aren’t guaranteed, but they are common.

Dermazen Calming Seborrheic Serum and Scalp Therapy Shampoo
A third-party clinical trial put Dermazen to the test — and the results speak for themselves.
92%
Flake-Free, Calm Scalp*

Over 92% of all participants in the study reported less dandruff, flakiness, and irritation.*

100%
Increase In Scalp Comfort*

Participants reported feeling more than twice as soothed and calm on their scalp after using Dermazen daily.*

Our 3-Step Process to Calm Your Skin

1. Disrupt the Biofilm

The fungus causing your moody skin is protected by a biofilm shield. Our unique formula safely disrupts this outer layer, exposing the fungus to Step #2.

2. Clear Away the Fungus

Once the biofilm is gone, you'll want to get rid of the fungus itself. We clear it out with a symphony of natural ingredients like tea tree, MSM (organic sulfur), sea salt, and more.

3. Soothe without Oils

The final step is to calm irritation and hydrate your skin without fungus-feeding oils. Aloe vera, niacinamide (vitamin B3), urea, and sodium hyaluronate (aka hyaluronic acid) bring the peace you're looking for.

Dermatologist Recommended

“I have been recommending the Calming Seborrheic Serum to people struggling with seborrheic dermatitis and psoriasis and they have seen significant improvement in their skin.”

- Dr. Maria Bonilla

What’s Inside

Aloe Leaf Juice

Helps soothe irritated scalp and signs of irritation

Xylitol

Works to naturally disrupt the biofilm layer and reduce signs of fungus

Grapefruit Seed Extract

Helps to calm moody scalps and support healthy hair and skin

Tea Tree Essential Oil

Helps calm and reduce signs of inflammation and fungus

Keeping it Zen

We practice ingredient minimalism. Our goal is to keep the list of ingredients humble while formulating products more effective than anything else. That’s why you won’t find parabens, sulfates, fragrances, or hard-to-pronounce chemicals. Those are the opposite of peaceful.

Zen Skin Trio

Zen Skin Trio

The foundation for malassezia skincare. The Zen Skin Trio is the perfect bundle to calm your scalp and face.

View Trio
Peaceful Skin System

Peaceful Skin System

The all-in-one system to soothe your flaky, red, and itchy face and scalp. Made by people with seborrheic dermatitis and recommended by dermatologists.

View System

How to Fix Your Flakes & Itching

I have textured hair.

I have straight/wavy hair.

  • 1

    Apply a generous amount of serum to your moody skin or scalp before bed, making sure to cover all of the affected area.

  • 2

    Massage in the formula as you thank your body for all its gifts.

  • 3

    In the morning*, rinse your hair with water or wash with a malassezia-safe shampoo before styling. If applied to the face, the soothing ingredients will absorb overnight.

  • 4

    Enjoy all-day peaceful skin and peace of mind.

*If you prefer to shower at night, just be sure to allow the serum to absorb into your scalp for at least two hours before rinsing or washing.

  • 1

    Apply the serum and massage it into your scalp and face thoroughly the night before (or at least two hours before) you plan to wash your hair - even if that is every week or two.

  • 2

    The serum can also be rinsed out with water (without shampoo) either with a full rinse or with a wet washcloth in between braids across the scalp.

  • 3

    Some folks with textured hair use the serum as a leave-in product, since the holistic ingredients will naturally absorb into the scalp for lasting relief.

4.5
Rated 4.5 out of 5 stars
Based on 1,592 reviews
Total 5 star reviews: 1.2k Total 4 star reviews: 193 Total 3 star reviews: 80 Total 2 star reviews: 40 Total 1 star reviews: 64
88%would recommend this product
Slide 1 selected
1,592 reviews
  • CG
    Chanell G.
    Verified Buyer
    I recommend this product
    Where did you need relief? Scalp
    What did this product help with? Flakes, Itching, Build-Up, Skin Health
    How old are you? 35-44
    What is your gender? Female
    What texture is your hair? Curly
    Rated 5 out of 5 stars
    19 seconds ago
    Best product on the market !

    We tried everything to tame our sensitive scalps and Dermazen is by far the only product, either RX or OTC, that works affectively and everytime !

  • AF
    Ashley F.
    Verified Buyer
    I recommend this product
    Where did you need relief? Face
    What did this product help with? Flakes
    How old are you? 18-24
    What is your gender? Female
    What texture is your hair? Curly
    Rated 5 out of 5 stars
    19 hours ago
    serum

    always works

  • IA
    Iman A.
    Verified Buyer
    I recommend this product
    Where did you need relief? Scalp
    What did this product help with? Flakes, Itching, Build-Up
    How old are you? 18-24
    What is your gender? Female
    What texture is your hair? Textured
    Rated 5 out of 5 stars
    Yesterday
    Improved Flakes

    literally the solution to my flakes. expensive but worth it

    D Profile picture for Dermazen
    Dermazen
    Yesterday

    Iman, we love hearing "literally the solution" from our customers—that's exactly what we want to be for your flakes!

    We know it's an investment, but there's nothing better than hearing that you feel it's been worth every penny for getting those flakes under control!

    Thank you for a perfect 5-star rating! You gave us the highest of praises! 💚😁

  • GH
    Gloria H.
    Verified Buyer
    I recommend this product
    Where did you need relief? Scalp
    What did this product help with? Flakes, Itching
    How old are you? 45-54
    What is your gender? Female
    What texture is your hair? Straight
    Rated 5 out of 5 stars
    2 days ago
    Using everyday - it works!

    I’ve been using this product everyday, and it has helped my flakiness, itchiness, and my flareups ! I’ve tried other serums and this one works for me!

    D Profile picture for Dermazen
    Dermazen
    Yesterday

    We love hearing "it works!" from our customers—music to our ears! not just 1 but 2 products worked for you! There's nothing better than hearing that daily use is bringing you consistent relief across all those areas that matter most! Thanks for giving us a chance! 💚✨

  • J
    Jermar
    I recommend this product
    Rated 4 out of 5 stars
    3 days ago
    4 Stars

    Once I used it on my scalp I could feel the relief of Dry scalp and the coolness at the same time

  • EF Profile picture for Erin F.
    Erin F.
    Verified Buyer
    I recommend this product
    Where did you need relief? Face
    What did this product help with? Flakes, Itching, Build-Up, Skin Tone, Skin Health
    How old are you? 45-54
    What is your gender? Female
    What texture is your hair? Straight
    Rated 5 out of 5 stars
    5 days ago
    My new fire hydrant!

    I use the serum on my face. I have had a problem with hormonal acne my whole adult life. In my perimenopausal years, the harsh cleansers and topicals I had always used were not doing their jobs and were causing new issues with Malassezia overgrowth. This product has finally helped put out the fire! My skin used to feel raw, tight, and itchy constantly, but now it feels calmer.

    D Profile picture for Dermazen
    Dermazen
    4 days ago

    Erin, what a perfect way to describe it—your new fire hydrant! We're absolutely happy to hear that the Calming Seborrheic Serum has been such a game-changer for putting out that fire and bringing you the relief you've been searching for. It sounds like you've been through quite the journey with hormonal changes and dealing with Malassezia overgrowth, so we're especially happy that our serum has been able to calm things down and give your skin the soothing comfort it needed. There's nothing better than hearing that raw, tight, itchy feeling has been replaced with calm, comfortable skin—that's exactly the kind of transformation we love to see! Thanks for sharing this experience! 💚✨🔥

  • JM Profile picture for Jorge M.
    Jorge M.
    Verified Buyer
    I recommend this product
    Where did you need relief? Face
    What did this product help with? Flakes, Itching, Skin Health, Build-Up
    How old are you? 18-24
    What is your gender? Male
    What texture is your hair? Straight
    Rated 5 out of 5 stars
    5 days ago
    Amazing! Works like a charm

    Immediately you feel relief. I would say about 1-2 days after applying on affected areas, twice a day, you see a noticeable difference. Almost all flakes and redness are gone after 1-2 days.

    D Profile picture for Dermazen
    Dermazen
    5 days ago

    Wow, that's fast relief! Thanks for sharing your results. We're delighted to hear that our product starts working in just 1-2 days, reducing flakes and redness. Your speedy recovery is music to our ears!🌱😊

  • AP Profile picture for Aisha P.
    Aisha P.
    Verified Buyer
    I recommend this product
    Where did you need relief? Scalp
    What did this product help with? Flakes, Itching, Build-Up
    How old are you? 45-54
    What is your gender? Female
    What texture is your hair? Curly
    Rated 5 out of 5 stars
    6 days ago
    Holy Grail for My Scalp! ⭐️⭐️⭐️⭐️⭐️

    I cannot say enough good things about this Calming Seborrheic Serum! After struggling for years with flakes, irritation, and stubborn seborrheic dermatitis, this serum has completely transformed my scalp health. Within just a few uses, my scalp was visibly clearer, less itchy, and so much calmer.

    What makes this even more of a win is how perfectly it works with my natural hairstyles—whether I’m rocking braids, a protective two-strand twist, or just wearing my curls out, this serum gets right to the root (literally!) without leaving buildup or ruining my style. It’s lightweight, soothing, and doesn’t interfere with any oils or creams I use in my routine.

    If you’re dealing with scalp issues, this serum is a must-have. I will never be without it again!

    D Profile picture for Dermazen
    Dermazen
    6 days ago

    Aisha, we're absolutely over the moon to hear the Calming Seborrheic Serum has become your holy grail! It's so incredible that after years of struggling with flakes and irritation, you've found something that's completely transformed your scalp health—that's exactly the kind of life-changing results we love to hear about! And we're especially thrilled that it works so beautifully with all your natural hairstyles, from braids to twist-outs to your gorgeous curls. The fact that it gets right to the root without any buildup or interference with your styling routine is just perfect—that's what makes it such a game-changer for so many of our customers! We love that it's lightweight and soothing while still delivering such powerful results. 💚🌱✨