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Bottle of Dermazen Calming Seborrheic Serum, 4 fl oz, with the text “Made by humans with moody skin” on the label.
Woman applying Dermazen Calming Seborrheic Serum to her scalp, with text “Safe for (curly, kinky, flat, and/or color treated) hair.”
Woman peacefully sleeping on white bed with text “Sleep your way to a clear scalp.”
Ingredient list for Calming Seborrheic Serum, including purified water, sea salt, colloidal silver, and essential oils.
Hand holding a bottle of Dermazen Calming Seborrheic Serum with text “Break the fungal biofilm, remove yeast naturally, stop the itching & flakes.”
Dermazen Calming Seborrheic Serum bottle with text: Steroid free, Toxin free, Prescription free, Worry free.
Woman with wet hair holding her head, text: “Amazing Results. My scalp is much happier (no more dandruff) and my thinning hair is noticeably fuller. - Dana H.”
Woman applying Dermazen Calming Seborrheic Serum to her scalp, text: “Dual Relief Formula: Targets the yeast causing your dandruff + Soothes your scalp right away.”
Hands holding and dispensing Dermazen Calming Seborrheic Serum, a drop falling into the palm.
Bottle of Dermazen Scalp Relief Serum on a light background with drops of the serum beside it.
Dermazen Calming Seborrheic Serum (8 fl oz) next to an open Cooling Rescue Roller (1 fl oz) on a white background.
Bottle of Dermazen Calming Seborrheic Serum, 8 fl oz, on a white background.
Calming Seborrheic Serum
  • Load image into Gallery viewer, Bottle of Dermazen Calming Seborrheic Serum, 4 fl oz, with the text “Made by humans with moody skin” on the label.
  • Load image into Gallery viewer, Woman applying Dermazen Calming Seborrheic Serum to her scalp, with text “Safe for (curly, kinky, flat, and/or color treated) hair.”
  • Load image into Gallery viewer, Woman peacefully sleeping on white bed with text “Sleep your way to a clear scalp.”
  • Load image into Gallery viewer, Ingredient list for Calming Seborrheic Serum, including purified water, sea salt, colloidal silver, and essential oils.
  • Load image into Gallery viewer, Hand holding a bottle of Dermazen Calming Seborrheic Serum with text “Break the fungal biofilm, remove yeast naturally, stop the itching & flakes.”
  • Load image into Gallery viewer, Dermazen Calming Seborrheic Serum bottle with text: Steroid free, Toxin free, Prescription free, Worry free.
  • Load image into Gallery viewer, Woman with wet hair holding her head, text: “Amazing Results. My scalp is much happier (no more dandruff) and my thinning hair is noticeably fuller. - Dana H.”
  • Load image into Gallery viewer, Woman applying Dermazen Calming Seborrheic Serum to her scalp, text: “Dual Relief Formula: Targets the yeast causing your dandruff + Soothes your scalp right away.”
  • Load image into Gallery viewer, Hands holding and dispensing Dermazen Calming Seborrheic Serum, a drop falling into the palm.
  • Load image into Gallery viewer, Bottle of Dermazen Scalp Relief Serum on a light background with drops of the serum beside it.
  • Load image into Gallery viewer, Dermazen Calming Seborrheic Serum (8 fl oz) next to an open Cooling Rescue Roller (1 fl oz) on a white background.
  • Load image into Gallery viewer, Bottle of Dermazen Calming Seborrheic Serum, 8 fl oz, on a white background.
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"This has been my holy grail. My scalp and face are calmer than they've been in years." - Samantha C., Repeat Customer

Calming Seborrheic Serum

4.5
Rated 4.5 out of 5 stars
1,478 Reviews

Soothe your scalp and face. This all-in-one serum helps disrupt the biofilm, clears away signs of fungus, and calms your skin naturally.

  1. Helps reduce and relieve signs of:
  2. Dandruff
  3. seborrheic dermatitis
  4. fungal conditions
  • Reduce flakes

  • Calm Redness

  • Soothe Itching

  • Safe for Malassezia

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Malassezia-Safe \ Color-Safe \ 60-Day Guarantee \ Sulfate-Free \ Vegan \ Steriod-Free \ All-Natural \ Dermatologist Recommended \ Malassezia-Safe \ Color-Safe \ 60-Day Guarantee \ Sulfate-Free \ Vegan \ Steriod-Free \ All-Natural \ Dermatologist Recommended \

The #1 Dandruff & Seborrheic Dermatitis Mistake

Why Moisturizing Will Never Be Enough

From Moody Skin to Peace of Mind

Every photo represents a life changed forever. The next chapter of your healing story can start today. Get relief with Dermazen and put your flare-ups and frustration behind you.

Results like these aren’t guaranteed, but they are common.

Our 3-Step Process to Calm Your Skin

1. Disrupt the Biofilm

The fungus causing your moody skin is protected by a biofilm shield. Our unique formula safely disrupts this outer layer, exposing the fungus to Step #2.

2. Clear Away the Fungus

Once the biofilm is gone, you'll want to get rid of the fungus itself. We clear it out with a symphony of natural ingredients like tea tree, MSM (organic sulfur), sea salt, and more.

3. Soothe without Oils

The final step is to calm irritation and hydrate your skin without fungus-feeding oils. Aloe vera, niacinamide (vitamin B3), urea, and sodium hyaluronate (aka hyaluronic acid) bring the peace you're looking for.

Why your dandruff shampoo has failed you

If your dandruff shampoo doesn’t target the biofilm protecting the fungus, it can never solve the root cause of your flakes and itching.

Plus, if your shampoo contains oils, then it’s feeding the fungus each time you shower.

Dermatologist Recommended

“I have been recommending the Calming Seborrheic Serum to people struggling with seborrheic dermatitis and psoriasis and they have seen significant improvement in their skin.”

- Dr. Maria Bonilla

What’s Inside

Aloe Leaf Juice

Helps soothe irritated scalp and signs of irritation

Xylitol

Works to naturally disrupt the biofilm layer and reduce signs of fungus

Grapefruit Seed Extract

Helps to calm moody scalps and support healthy hair and skin

Tea Tree Essential Oil

Helps calm and reduce signs of inflammation and fungus

Keeping it Zen

We practice ingredient minimalism. Our goal is to keep the list of ingredients humble while formulating products more effective than anything else. That’s why you won’t find parabens, sulfates, fragrances, or hard-to-pronounce chemicals. Those are the opposite of peaceful.

Zen Skin Trio

Zen Skin Trio

The foundation for malassezia skincare. The Zen Skin Trio is the perfect bundle to calm your scalp and face.

View Trio
Peaceful Skin System

Peaceful Skin System

The all-in-one system to soothe your flaky, red, and itchy face and scalp. Made by people with seborrheic dermatitis and recommended by dermatologists.

View System

How to Fix Your Flakes & Itching

I have textured hair.

I have straight/wavy hair.

  • 1

    Apply a generous amount of serum to your moody skin or scalp before bed, making sure to cover all of the affected area.

  • 2

    Massage in the formula as you thank your body for all its gifts.

  • 3

    In the morning*, rinse your hair with water or wash with a malassezia-safe shampoo before styling. If applied to the face, the soothing ingredients will absorb overnight.

  • 4

    Enjoy all-day peaceful skin and peace of mind.

*If you prefer to shower at night, just be sure to allow the serum to absorb into your scalp for at least two hours before rinsing or washing.

  • 1

    Apply the serum and massage it into your scalp and face thoroughly the night before (or at least two hours before) you plan to wash your hair - even if that is every week or two.

  • 2

    The serum can also be rinsed out with water (without shampoo) either with a full rinse or with a wet washcloth in between braids across the scalp.

  • 3

    Some folks with textured hair use the serum as a leave-in product, since the holistic ingredients will naturally absorb into the scalp for lasting relief.

4.5
Rated 4.5 out of 5 stars
Based on 1,478 reviews
Total 5 star reviews: 1.1k Total 4 star reviews: 185 Total 3 star reviews: 73 Total 2 star reviews: 37 Total 1 star reviews: 60
88%would recommend these products
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1,478 reviews
  • JT
    John T.
    Verified Buyer
    Reviewing
    Calming Seborrheic Serum
    I recommend this product
    Where did you need relief? Scalp
    What did this product help with? Flakes, Itching, Build-Up, Skin Tone
    How old are you? 25-34
    What is your gender? Male
    What texture is your hair? Other
    Rated 5 out of 5 stars
    4 hours ago
    Works

    It works well surprisingly

  • B Profile picture for Bonds
    Bonds
    Verified Reviewer
    Reviewing
    Calming Seborrheic Serum
    I recommend this product
    Where did you need relief? Scalp
    What did this product help with? Flakes, Itching, Build-Up
    How old are you? 35-44
    What is your gender? Female
    What texture is your hair? Curly
    Rated 5 out of 5 stars
    2 days ago
    Dermazen is my scalp’s best friend!

    #Dermazen literally literally saved my #scalp! Those who know my previous scalp issues, know I swear by this brand! #Healing

    I visited 2 #Dermatologist and a #trichologist (scalp specialist) none of the three specialist resolved my scalp issue, then I found #Dermazen

    SAVED me! #hair #scalp #sebhorreicdermatitis

    The pics are before, the video is after!

  • RJ
    Royce J.
    Verified Buyer
    Reviewing
    Calming Seborrheic Serum
    I recommend this product
    Where did you need relief? Body, Ears, Scalp
    What did this product help with? Flakes, Build-Up, Skin Tone, Itching
    How old are you? 25-34
    What is your gender? Female
    What texture is your hair? Textured
    Rated 5 out of 5 stars
    1 week ago
    Super helpful

    I’ve been using for a month and it’s helped calm my slate ups so much!

    D Profile picture for Dermazen
    Dermazen
    1 week ago

    We're absolutely thrilled to hear about your incredible experience with our products, Royce! It's amazing to know that you've seen such wonderful improvement with your flare-ups over the past month. Thank you for giving our product a chance and for sharing your journey with us! 💚

  • JR
    Joy R.
    Verified Buyer
    Reviewing
    Calming Seborrheic Serum
    I recommend this product
    Where did you need relief? Scalp
    What did this product help with? Flakes, Itching, Build-Up
    How old are you? Under 18
    What is your gender? Female
    What texture is your hair? Straight
    Rated 5 out of 5 stars
    2 weeks ago
    Getting Better by can’t quit the product or the diet or the vitamin b

    This product is maybe not a stand alone cure for my daughter but has made a world of difference. She struggled more with flakes than consistent redness. When she first started this product she had lots of little ‘pimples’ on her scalp-most noticeably on the sides of her scalp and near her forehead hairline, likely from her head resting on her head often. As a teenager it’s hard enough to make it through school and extracurriculars in one mental piece much less with flakes all over her shoulders and her scalp itching horrendously. She’s been on this product for over a year and it has improved drastically. There aren’t anymore pimples on her head and her flakes are on average 10-15% of what they used to be. Changing her pillowcase every time she washes her hair, washing her hairbrush each time she washes her hair, and taking B vitamins in tandem has kept her flakes at bay. We did realize when she ran out of the serum that her flakes worsened. You can’t really sub in another hair product for any of them for her. It gets really expensive and our entire hope was to heal the body and the guts and not need such an expensive lineup, but I don’t think we’ll get that lucky. So: be warned: it may help, but you may be on it for life! Photo is of hair washed yesterday with just 1-4 flakes in the photo. When she started it would’ve looked like a snowstorm.

    D Profile picture for Dermazen
    Dermazen
    1 week ago

    We're absolutely thrilled to hear about your daughter's incredible journey with our products! It's amazing to know how much improvement she's seen over the past year. We completely understand the challenges teenagers face, and we're so glad our product has helped make things easier for her. Thank you for sharing your daughter's detailed experience and ongoing success story with us! 🤗

  • MH
    Michelle H.
    Verified Buyer
    Reviewing
    Calming Seborrheic Serum Cloths
    I recommend this product
    Where did you need relief? Face, Scalp, Body
    What did this product help with? Skin Health, Itching, Build-Up
    How old are you? 45-54
    What is your gender? Female
    What texture is your hair? Wavy
    Rated 5 out of 5 stars
    3 weeks ago
    Great fit in between

    Love these wipes love all the products game changer

    D Profile picture for Dermazen
    Dermazen
    3 weeks ago

    Thank you so much for your kind words! It means the world to us that our wipes—and all of our products—have been a game changer for you. There’s no better feeling than knowing we’ve helped make your routine easier and more enjoyable! 🥳

  • EV
    evelyn v.
    Verified Buyer
    Reviewing
    Calming Seborrheic Serum
    I recommend this product
    Where did you need relief? Scalp
    What did this product help with? Build-Up, Itching, Skin Health, Flakes
    How old are you? Over 65
    What is your gender? Female
    What texture is your hair? Curly
    Rated 5 out of 5 stars
    3 weeks ago
    This serum actually helped soothe my crusty scalp! Great to calm the eczema

    Easy to use and I love the herbal scent

    D Profile picture for Dermazen
    Dermazen
    3 weeks ago

    We’re over the moon to hear our serum helped soothe your scalp and calm your eczema—nothing makes us happier than knowing our products bring real relief! We love that you’re enjoying the herbal scent, too. Your positive feedback means a lot to us and helps others feel confident giving it a try. Cheers to peaceful skin!🥂

  • CS
    Chelsey S.
    Verified Buyer
    Reviewing
    Calming Seborrheic Serum
    I recommend this product
    Where did you need relief? Scalp
    What did this product help with? Flakes, Itching, Build-Up
    How old are you? 35-44
    What is your gender? Female
    What texture is your hair? Wavy
    Rated 5 out of 5 stars
    1 month ago
    Finally, a real solution

    I have struggled with dandruff and worsening seborrheic dermatitis for years. The combination of the treatment plus the shampoo cleared everything up in about 3 washes. I also really love how limited and simple the ingredients are. The picture is my greasy hair 1 week out from washing. Still no flakes. So incredibly grateful!

    D Profile picture for Dermazen
    Dermazen
    1 month ago

    Chelsey, we're absolutely elated to hear about the incredible results you've experienced with our products! Thank you for trusting us to be a part of your journey and for being a valued member of our community. Your positive review means everything to us 🌿

  • MB
    Mugabi B.
    Verified Buyer
    Reviewing
    Calming Seborrheic Serum
    I recommend this product
    Where did you need relief? Scalp
    What did this product help with? Flakes, Build-Up
    How old are you? 25-34
    What is your gender? Something else
    What texture is your hair? Curly
    Rated 5 out of 5 stars
    1 month ago
    Works like a charm

    I tried this from an Instagram video showing that it worked on Black hair and after a few days my dandruff which had antagonized me for years cleared up! Worked like a charm and will continue using it!

    D Profile picture for Dermazen
    Dermazen
    1 month ago

    This made our day! We’re so glad you found relief and that it’s been a great fit for your routine. Thank you for trusting us with your scalp concerns, Mugabi! 🤗