Calming Seborrheic Serum
Calming Seborrheic Serum

60-Day Peaceful Skin Guarantee

"This has been my holy grail. My scalp and face are calmer than they've been in years." - Samantha C., Repeat Customer

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Calming Seborrheic Serum

424 reviews

Enjoy peaceful skin and peace of mind. This all-in-one serum clears away malassezia fungus while soothing irritated skin. Provides relief for the scalp, face, and body.

  • Reduce flakes

  • Calm Redness

  • Soothe Itching

  • Safe for Malassezia

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60-Day Peaceful Skin Guarantee

"This has been my holy grail. My scalp and face are calmer than they've been in years." - Samantha C., Repeat Customer


I'm soooo grateful for these products !!! I've been dealing with painful oozing eczema on my face...

Ibeth q.

First of all, I want to thank the creators of this product (and the guidebook) which is as import...

Tiffany P.

Listen here y'all! I don't even know where to begin... About a year ago my scalp started busting ...


After YEARS of trying everything from soaps to lotions to creams and steroids, I finally found so...

Rana M.

So far, this product has been the one to help calm the redness and itchiness of my scalp. I’ve tr...

Mikhail G.

Works beautifully with my skin.

Isabella S.

Almost a month in using this serum, and I am loving it. After four months of dealing with this de...

Alyssa K.

I had suffered with redness scaly skin around my nose, mouth, and brows, ad well as on my scalp. ...

Why It Works: Our 3-Step Process

1. Disrupt the Biofilm

Malassezia creates a biofilm shield that protects it from antifungal treatment. We’ve unlocked the secret to safely neutralize this barrier.

2. Clear the Fungus

Once the biofilm is removed, you can clear away the fungus easier than ever. We use skin-safe antifungals powered by Mother Nature.

3. Soothe the Skin

Now it’s time to nourish and hydrate your skin without using lipids (like coconut oil) that feed the malassezia. That's what makes every Dermazen formula Malassezia Safe.

Trusted By Experts

“I have been recommending the Calming Seborrheic Serum to my patients with seborrheic dermatitis and psoriasis and they have seen significant improvement in their skin.”

- Dr. Maria Bonilla

What’s Inside

200x Concentrated Aloe

Soothe your irritated scalp and calm inflamed skin


Naturally disrupt the biofilm layer to weaken the fungus

Grapefruit Seed Extract

Eliminate fungus and boost antioxidants

Tea Tree Essential Oil

Calm inflammation and eliminate fungus

Keeping it Zen

We practice ingredient minimalism. Our goal is to keep the list of ingredients humble while formulating products more effective than anything else. That’s why you won’t find parabens, sulfates, fragrances, or hard-to-pronounce chemicals. Those are the opposite of peaceful.

What Others Are Saying

The Peaceful Skin Guarantee

We removed all the risk. If you aren’t amazed at the results, send us an email within 60 days and we’ll send you a full refund.

Zen Skin Trio

The the foundation for malassezia skincare. The Zen Skin Trio is the perfect bundle to calm your scalp and face.

View Trio

Soothing Malassezia Moisturizer

This gentle moisturizer provides deep hydration, skin tone balancing, skin barrier protection, and relief from facial flaking.

View Moisturizer

How to use it

  • 1

    Start by applying a generous amount of the serum to your skin.

  • 2

    Massage in the formula as you thank your body for all its hard work.

  • 3

    Allow the serum to absorb fully. You may wash off the serum after a few hours, but it's safe to leave on all day or night.

  • 4

    If you’d like, use the serum twice a day for faster relief.

  • 5

    Finally, enjoy the peace of mind brought to you by peaceful skin.

Customer Reviews
4.6 Based on 424 Reviews
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Great Relief but quickly used

I love it. It instantly relieved me. I paired it with the shampoo, and everything is gone! I love it, and It has natural ingredients. When it dries, it is pretty ok if you do not saturate your scalp to leave your hair looking clean.

Elisa C.
United States United States

Great product

It’s easy to use and take along with you

Emily I.
United States United States

Want it to work

For me it had a real burning sensation when on the skin. I am fair skinned so this may be a factor. It is especially noticeable on the scalp to the point of discomfort. Of course this is the main area I purchased it to help with. It has a scent of Tea Tree this could be causing the burning- it is more tolerable on one spot on my hand. No real difference in redness so far.

Vince W.
United States United States

Works Great!

Leaves hair a little oily so have to wash it out the next morning but scalp is less itchy and seems to help hair growth as well!

Ashley D.
United States United States

Give it time

My Seborrheic Derm in mostly on my nose, in between my eyebrows, and often most intense on the sides of my nose. I found this calming serum to work great but had to get it figured out. It was too strong for my skin to put on daily at full strength. I diluted it 50/50 with purified water and backed off to once a day. I actually use it in the morning after I shower. I clean my face (mostly just that region) at night with a cleanser from another Seb. Derm company, but then use the Dermazen Moisturizer as soon as my face is dry. The combination of the two have been a game changer. I face is pretty darn clear now and a lot less red, sometimes not at all. It probably took me two weeks to get it all figured out so be patient. If your face is getting worse or more red from using this product then you probably need to dilute, back off frequency, or both. Just my opinion. Glad I found it.

Aaron M.
United States United States

Finally Relief

I haven't been using this too long, but I do believe it is making a difference. I'm going to keep on it and hopefully see more improvement. I'm not able to just use it once a week yet, but I do feel it's making a difference.

Dawn R.
United States United States

Not working yet?

I have used DERmazem twice a da for several days for Seborrheic Dermatitis in the nano labial folds. The skin is still red- not itchy just red. long does it take to work?

Elyse K.
United States United States


I've only been using this serum for a week but I have noticed a big difference! My scalp is less itchy, there's fewer flakes, and it feels like the damage that seborrheic dermatitis caused to my scalp is slowly but surely repairing itself. It's not an overnight cure by any means but you will see results upon first using it. I'm excited to see where I am months down the line if I'm already seeing such great results a week in. :) Would definitely purchase again, and I think it's worth the buy.

United States United States

Definitely helped

This is the best product that I've used that is actually helped the most. Thank you

Jacob L.
United States United States

Great product

I love this product, not only does it provide soothing effects as soon as applied to my skin but it also reduced the redness and flaking of my skin over the course of a month. Previously, I had flaking skin on my face that was vert noticeable after applying moisturizer and sunscreen. Now I can finish my skincare routine with confidence!

Eliz C.
United States United States

Good Stuff, just a bit pricey

I love this product, I just wish I got more for my money.

United States United States

Happy Skin - Finally!

This is the best product I've come across to treat sebderm. Although it took me a few weeks to find my rhythm using the Calming Serum, my skin has achieved a balance where I don't have to use it every day. It's most effective as a scalp treatment (no more itch!) and on/behind my ears, too. It's pricey, but after years of troubleshooting with various products--OTC and prescription ($$$) with lackluster results--Dermazen is totally worth every penny. I'm sold!

Regina M.
United States United States