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Bottle of Dermazen Calming Seborrheic Serum, 4 fl oz, with the text “Made by humans with moody skin” on the label.
Woman applying Dermazen Calming Seborrheic Serum to her scalp, with text “Safe for (curly, kinky, flat, and/or color treated) hair.”
Woman peacefully sleeping on white bed with text “Sleep your way to a clear scalp.”
Ingredient list for Calming Seborrheic Serum, including purified water, sea salt, colloidal silver, and essential oils.
Hand holding a bottle of Dermazen Calming Seborrheic Serum with text “Break the fungal biofilm, remove yeast naturally, stop the itching & flakes.”
Dermazen Calming Seborrheic Serum bottle with text: Steroid free, Toxin free, Prescription free, Worry free.
Woman with wet hair holding her head, text: “Amazing Results. My scalp is much happier (no more dandruff) and my thinning hair is noticeably fuller. - Dana H.”
Woman applying Dermazen Calming Seborrheic Serum to her scalp, text: “Dual Relief Formula: Targets the yeast causing your dandruff + Soothes your scalp right away.”
Hands holding and dispensing Dermazen Calming Seborrheic Serum, a drop falling into the palm.
Bottle of Dermazen Scalp Relief Serum on a light background with drops of the serum beside it.
Dermazen Calming Seborrheic Serum (8 fl oz) next to an open Cooling Rescue Roller (1 fl oz) on a white background.
Bottle of Dermazen Calming Seborrheic Serum, 8 fl oz, on a white background.
Calming Seborrheic Serum
  • Load image into Gallery viewer, Bottle of Dermazen Calming Seborrheic Serum, 4 fl oz, with the text “Made by humans with moody skin” on the label.
  • Load image into Gallery viewer, Woman applying Dermazen Calming Seborrheic Serum to her scalp, with text “Safe for (curly, kinky, flat, and/or color treated) hair.”
  • Load image into Gallery viewer, Woman peacefully sleeping on white bed with text “Sleep your way to a clear scalp.”
  • Load image into Gallery viewer, Ingredient list for Calming Seborrheic Serum, including purified water, sea salt, colloidal silver, and essential oils.
  • Load image into Gallery viewer, Hand holding a bottle of Dermazen Calming Seborrheic Serum with text “Break the fungal biofilm, remove yeast naturally, stop the itching & flakes.”
  • Load image into Gallery viewer, Dermazen Calming Seborrheic Serum bottle with text: Steroid free, Toxin free, Prescription free, Worry free.
  • Load image into Gallery viewer, Woman with wet hair holding her head, text: “Amazing Results. My scalp is much happier (no more dandruff) and my thinning hair is noticeably fuller. - Dana H.”
  • Load image into Gallery viewer, Woman applying Dermazen Calming Seborrheic Serum to her scalp, text: “Dual Relief Formula: Targets the yeast causing your dandruff + Soothes your scalp right away.”
  • Load image into Gallery viewer, Hands holding and dispensing Dermazen Calming Seborrheic Serum, a drop falling into the palm.
  • Load image into Gallery viewer, Bottle of Dermazen Scalp Relief Serum on a light background with drops of the serum beside it.
  • Load image into Gallery viewer, Dermazen Calming Seborrheic Serum (8 fl oz) next to an open Cooling Rescue Roller (1 fl oz) on a white background.
  • Load image into Gallery viewer, Bottle of Dermazen Calming Seborrheic Serum, 8 fl oz, on a white background.
  • Load image into Gallery viewer, Calming Seborrheic Serum

"This has been my holy grail. My scalp and face are calmer than they've been in years." - Samantha C., Repeat Customer

Calming Seborrheic Serum

4.6
Rated 4.6 out of 5 stars
1,444 Reviews

Soothe your scalp and face. This all-in-one serum disrupts the biofilm, clears away fungus, and calms your skin naturally.

  1. Helps with:
  2. Dandruff
  3. seborrheic dermatitis
  4. fungal conditions
  • Reduce flakes

  • Calm Redness

  • Soothe Itching

  • Safe for Malassezia

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Malassezia-Safe \ Color-Safe \ 60-Day Guarantee \ Sulfate-Free \ Vegan \ Steriod-Free \ All-Natural \ Dermatologist Recommended \ Malassezia-Safe \ Color-Safe \ 60-Day Guarantee \ Sulfate-Free \ Vegan \ Steriod-Free \ All-Natural \ Dermatologist Recommended \

The #1 Dandruff & Seborrheic Dermatitis Mistake

Why Moisturizing Will Never Be Enough

From Moody Skin to Peace of Mind

Every photo represents a life changed forever. The next chapter of your healing story can start today. Get relief with Dermazen and put your flare-ups and frustration behind you.

Results like these aren’t guaranteed, but they are common.

Our 3-Step Process to Calm Your Skin

1. Disrupt the Biofilm

The fungus causing your moody skin is protected by a biofilm shield. Our unique formula safely disrupts this outer layer, exposing the fungus to Step #2.

2. Clear Away the Fungus

Once the biofilm is gone, you’ll want to get rid of the fungus itself. We clear it out with a symphony of natural ingredients like grapefruit seed extract, tea tree, organic sulfur, sea salt, and more.

3. Soothe without Oils

The final step is to calm irritation and hydrate your skin without fungus-feeding oils. Aloe vera, vitamin B3, urea, and hyaluronic acid bring the peace you’re looking for.

Why your dandruff shampoo has failed you

If your dandruff shampoo doesn’t target the biofilm protecting the fungus, it can never solve the root cause of your flakes and itching.

Plus, if your shampoo contains oils, then it’s feeding the fungus each time you shower.

Dermatologist Recommended

“I have been recommending the Calming Seborrheic Serum to my patients with seborrheic dermatitis and psoriasis and they have seen significant improvement in their skin.”

- Dr. Maria Bonilla

What’s Inside

200x Concentrated Aloe

Soothe your irritated scalp and calm inflamed skin

Xylitol

Naturally disrupt the biofilm layer to weaken the fungus

Grapefruit Seed Extract

Eliminate fungus and boost antioxidants

Tea Tree Essential Oil

Calm inflammation and eliminate fungus

Keeping it Zen

We practice ingredient minimalism. Our goal is to keep the list of ingredients humble while formulating products more effective than anything else. That’s why you won’t find parabens, sulfates, fragrances, or hard-to-pronounce chemicals. Those are the opposite of peaceful.

Zen Skin Trio

Zen Skin Trio

The the foundation for malassezia skincare. The Zen Skin Trio is the perfect bundle to calm your scalp and face.

View Trio
Peaceful Skin System

Peaceful Skin System

The all-in-one system to soothe your flaky, red, and itchy face and scalp. Made by people with seborrheic dermatitis and recommended by dermatologists.

View System

How to Fix Your Flakes & Itching

I have textured hair.

I have straight/wavy hair.

  • 1

    Apply a generous amount of serum to your moody skin or scalp before bed, making sure to cover all of the affected area.

  • 2

    Massage in the formula as you thank your body for all its gifts.

  • 3

    In the morning*, rinse your hair with water or wash with a malassezia-safe shampoo before styling. If applied to the face, the soothing ingredients will absorb overnight.

  • 4

    Enjoy all-day peaceful skin and peace of mind.

*If you prefer to shower at night, just be sure to allow the serum to absorb into your scalp for at least two hours before rinsing or washing.

  • 1

    Apply the serum and massage it into your scalp and face thoroughly the night before (or at least two hours before) you plan to wash your hair - even if that is every week or two.

  • 2

    The serum can also be rinsed out with water (without shampoo) either with a full rinse or with a wet washcloth in between braids across the scalp.

  • 3

    Some folks with textured hair use the serum as a leave-in product, since the holistic ingredients will naturally absorb into the scalp for lasting relief.

4.6
Rated 4.6 out of 5 stars
Based on 1,444 reviews
Total 5 star reviews: 1.1k Total 4 star reviews: 185 Total 3 star reviews: 69 Total 2 star reviews: 33 Total 1 star reviews: 56
89%would recommend these products
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1,444 reviews
  • MB
    Mugabi B.
    Verified Buyer
    Calming Seborrheic Serum
    Reviewing
    Calming Seborrheic Serum
    I recommend this product
    Where did you need relief? Scalp
    What did this product help with? Flakes, Build-Up
    How old are you? 25-34
    What is your gender? Something else
    What texture is your hair? Curly
    Rated 5 out of 5 stars
    12 hours ago
    Works like a charm

    I tried this from an Instagram video showing that it worked on Black hair and after a few days my dandruff which had antagonized me for years cleared up! Worked like a charm and will continue using it!

    D Profile picture for Dermazen
    Dermazen
    53 minutes ago

    This made our day! We’re so glad you found relief and that it’s been a great fit for your routine. Thank you for trusting us with your scalp concerns, Mugabi! 🤗

  • AM
    Amanda M.
    Verified Buyer
    Calming Seborrheic Serum
    Reviewing
    Calming Seborrheic Serum
    I recommend this product
    Where did you need relief? Scalp
    What did this product help with? Flakes
    Rated 5 out of 5 stars
    4 days ago
    Soothing

    Very soothing to my dry scalp

    D Profile picture for Dermazen
    Dermazen
    3 days ago

    We’re so happy to hear our product is providing soothing relief for your dry scalp. Cheers to a stress free scalp!

  • VE
    Vanessa E.
    Verified Buyer
    Calming Seborrheic Serum
    Reviewing
    Calming Seborrheic Serum
    I recommend this product
    Where did you need relief? Scalp, Ears
    What did this product help with? Flakes, Itching
    How old are you? 35-44
    What is your gender? Female
    What texture is your hair? Wavy
    Rated 4 out of 5 stars
    1 week ago
    Works well but needs time

    It works well and helped to decrease the itching significantly. However, I made the mistake of only buying one bottle and I think it needs more time to work due to how severe my scalp condition is. The cold weather isn’t helping either. But the attached picture of my scalp, albeit still flaky, is significantly reduced in comparison to before. It’s not magic but works better than anything else I’ve tried. For me, there is an initial burning sensation upon application, but it subsides after a minute. I let it sit for about an hour before I go to bed so that it can soak in better, rather than it getting my pillow wet if I put in on right before sleeping.

    D Profile picture for Dermazen
    Dermazen
    1 week ago

    Sounds like you got your routine down pat, and that's amazing! I hope that the next time you leave a review, you'll be saying that the flakes are already under control. 😌🌱

  • LP
    Lindsay P.
    Verified Buyer
    Calming Seborrheic Serum
    Reviewing
    Calming Seborrheic Serum
    I recommend this product
    Where did you need relief? Scalp, Ears
    What did this product help with? Build-Up, Other
    How old are you? 25-34
    What is your gender? Female
    What texture is your hair? Curly
    Rated 5 out of 5 stars
    1 week ago
    Helped with flare up

    I have a severe case of seb derm on my entire scalp. I went through a very stressful time and had (am having?) a bad flare up. The first picture is on Dec 10, shortly before I started using the serum, and the second one is today. I am still struggling with a lot of flakes and some itching but my scalp does not hurt. In the first picture my entire scalp was on fire 24/7 and I lost some hair. After 4 days my scalp thankfully no longer hurt. I will keep using it—considering how severe my case is and how much pain I was in I am happy with the progress. I have extreme build up so in a way the flakes are a relief. I really wish there was a trial size or travel size of the shampoo and conditioner!

    D Profile picture for Dermazen
    Dermazen
    1 week ago

    Wow, Lindsay! That looks like a significant progress. I can see the redness has subsided. My fave part of this review is this: "After 4 days my scalp thankfully no longer hurt." It's a treat for the eyes. May you find more relief from sebderm 2025!!! ✨☺️

  • HS Profile picture for Heather S.
    Heather S.
    Verified Buyer
    Calming Seborrheic Serum
    Reviewing
    Calming Seborrheic Serum
    I recommend this product
    Where did you need relief? Scalp, Face, Ears
    What did this product help with? Flakes, Itching, Skin Health
    How old are you? 35-44
    What is your gender? Female
    What texture is your hair? Textured
    Rated 5 out of 5 stars
    1 week ago
    Love it!

    After 2 days of use, my scalp felt calmer and I stopped wanting to scratch my skin off. Will be ordering the MCT scalp moisturizer next!

    D Profile picture for Dermazen
    Dermazen
    1 week ago

    Heather, we're so thrilled to hear that the products have been able to soothe your scalp. Thank you for sharing your amazing progress with us so far. We can't wait to hear how the MCT Scalp Moisturizer works for you as well! We're incredibly grateful to have you as part of our Dermazen community. 💚

  • SN Profile picture for Shadrack N.
    Shadrack N.
    Verified Buyer
    Calming Seborrheic Serum
    Reviewing
    Calming Seborrheic Serum
    I recommend this product
    Where did you need relief? Scalp
    What did this product help with? Flakes, Itching, Build-Up
    How old are you? 25-34
    What is your gender? Male
    What texture is your hair? Curly
    Rated 5 out of 5 stars
    1 week ago
    Great product

    I'm not trying to be cliché, but I've got locs and I've been using this product for a while now. At first, I was a bit skeptical about it, but after using it for the past 6 months, I can honestly say that my hair has been growing faster and I haven't seen any flakes at all. I highly recommend it!

    D Profile picture for Dermazen
    Dermazen
    1 week ago

    Shadrack, we're absolutely delighted to hear about the amazing results you've had with our products! Thank you for trusting us on your journey and for taking the time to share your incredible experience. We're so grateful to have you as part of our community. Your recommendation means the world! 🙌

  • MA
    Mariyam a.
    Verified Buyer
    Calming Seborrheic Serum
    Reviewing
    Calming Seborrheic Serum
    I recommend this product
    Where did you need relief? Scalp
    What did this product help with? Flakes, Itching
    How old are you? 25-34
    What is your gender? Female
    What texture is your hair? Wavy
    Rated 5 out of 5 stars
    2 weeks ago
    Love it fir my flaky scalp

    It does the work

    D Profile picture for Dermazen
    Dermazen
    2 weeks ago

    It sure does, Mariyam! Thank you for your review and being apart of our community 💚

  • MS
    Malcolm S.
    Verified Buyer
    Calming Seborrheic Serum
    Reviewing
    Calming Seborrheic Serum
    I recommend this product
    Where did you need relief? Face, Scalp
    What did this product help with? Flakes, Itching, Build-Up, Skin Tone, Skin Health
    How old are you? 25-34
    What is your gender? Male
    What texture is your hair? Wavy
    Rated 5 out of 5 stars
    2 weeks ago
    IT WORKS !!!

    I will admit I was initially skeptical, but this products works as promised! I’ve dealt with seborrheic dermatitis for years and I’ve tried many prescription creams, shampoos, and topical solutions that did not work. It’s been about three weeks and I’d say it’s eliminated about 85% of my issues. I will be repurchasing for maintenance purposes.

    D Profile picture for Dermazen
    Dermazen
    2 weeks ago

    We're so glad you gave us a try even though you had some skepticism at first, Malcolm! We know trying products can be frustrating, but it's awesome that you're starting to get relief just after 3 weeks. Thank you for your incredible review and being apart of our community 🤗

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