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Soothe your beautiful, irritated skin

Holistic ingredients designed to calm the flakes, flare ups, and frustration caused by Malassezia fungus.
4.3
Rated 4.3 out of 5 stars
Based on 240 reviews
Total 5 star reviews: 163 Total 4 star reviews: 30 Total 3 star reviews: 17 Total 2 star reviews: 4 Total 1 star reviews: 26
80%would recommend this product
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240 reviews
  • KG Profile picture for kristin g.
    kristin g.
    Verified Buyer
    I recommend this product
    Where did you need relief? Scalp
    What did this product help with? Flakes, Itching, Build-Up
    How old are you? 35-44
    What is your gender? Female
    What texture is your hair? Straight
    Rated 5 out of 5 stars
    1 week ago
    Flaky scalp relief!

    This honestly is such a blessing to have found this product. Both my daughter and I suffer from extremely flaky scalps which is both uncomfortable and embarrassing. So thankful to have found this serum and shampoo. Ty for making a non toxic product that works! Repeat customer for sure.

    D Profile picture for Dermazen
    Dermazen
    1 week ago

    We're absolutely thrilled to hear about your incredible experience with our Scalp Relief System, Kristin! It means so much to us that both you and your daughter have found relief from those uncomfortable flaky scalp issues. Thank you for sharing your journey with us and for your continued trust in our products! 🤗

  • CM
    C M.
    Verified Buyer
    I recommend this product
    Where did you need relief? Scalp
    What did this product help with? Flakes, Build-Up, Skin Health
    What texture is your hair? Textured
    Rated 5 out of 5 stars
    1 week ago
    Amazing for my scalp!

    I had some painful dermatitis on my scalp and this formula soothed it almost completely! I’m so grateful to have found this product ✨

    D Profile picture for Dermazen
    Dermazen
    2 days ago

    We're absolutely thrilled to hear about your incredible experience with our products. We're grateful you found us and have gotten significant relief! 💚

    Thank you for sharing your journey with us and being part of our community! 🤗

  • MT
    Matthew T.
    Verified Buyer
    I recommend this product
    Where did you need relief? Scalp
    What did this product help with? Flakes, Itching
    How old are you? 25-34
    What is your gender? Male
    What texture is your hair? Straight
    Rated 5 out of 5 stars
    2 weeks ago
    Saved my hair

    This stuff literally stopped my dandruff within a day. I was skeptical and thought it wasn’t going to work. Saw results after one day of using the serum and shampoo for dandruff.

  • KC
    Kenneth C.
    Verified Buyer
    I recommend this product
    Where did you need relief? Scalp
    What did this product help with? Flakes, Itching, Build-Up
    How old are you? 25-34
    What is your gender? Male
    What texture is your hair? Textured
    Rated 5 out of 5 stars
    3 weeks ago
    Definitely surprised me

    I’m definitely surprised with the efficacy of the serum. I wasn’t expecting much, honestly. Most products say that they treat seborrheic dermatitis, but end up being essentially useless. I actually saw results with the serum. In 1-2 most of the itching and flaking was gone or drastically decreased. When I went to get my hair done, there weren’t flakes snowing down from my scalp. I’m satisfied thus far, even though it is relatively expensive.

    D Profile picture for Dermazen
    Dermazen
    3 weeks ago

    We're absolutely thrilled to hear about your incredible experience with our Scalp Relief System, Kenneth! It's amazing to know that you've seen such dramatic improvements with your seborrheic dermatitis in just a matter of days. Thank you for giving our products a chance and for sharing your journey with us! 💚

  • RJ
    Royce J.
    Verified Reviewer
    I recommend this product
    Where did you need relief? Body, Ears, Scalp
    What did this product help with? Flakes, Build-Up, Skin Tone, Itching
    How old are you? 25-34
    What is your gender? Female
    What texture is your hair? Textured
    Rated 5 out of 5 stars
    3 weeks ago
    Only topical treatment that has given me relief

    I’ve only been using for a month and I’m seeing a tremendous improvement wi the my flakiness. My flare ups are returning back to their skin tone .

    D Profile picture for Dermazen
    Dermazen
    3 weeks ago

    Thank you for sharing your experience! We’re thrilled that our product has been the only topical treatment to give you relief and help return those flare-ups closer to your natural skin tone. Keep us posted on your continued progress, and don’t hesitate to reach out if you have any questions. We’re here to support you every step of the way!

  • LC Profile picture for lexy c.
    lexy c.
    Verified Buyer
    I do not recommend this product
    Where did you need relief? Scalp, Face, Ears, Body
    What did this product help with? Other
    How old are you? 18-24
    What is your gender? Female
    What texture is your hair? Straight
    Rated 1 out of 5 stars
    1 month ago
    Not good for me

    This did absolutely nothing but inflame my scalp more. I’ve used it as directed and my scalp only feels worse, I feel very deceived especially for almost $100 :( very unfortunate, really wanted to live this & for it to work.

    D Profile picture for Dermazen
    Dermazen
    1 month ago

    We're truly sorry to hear that our products didn't bring you the relief you were hoping for, Lexy, and that your scalp condition isn't improving. Please feel free to reach out to us directly at support@dermazen.co so we can further assist you and explore options to find a resolution. 🙏

  • LP
    Lindsay P.
    Verified Buyer
    I recommend this product
    Where did you need relief? Scalp, Ears
    What did this product help with? Other, Flakes, Itching, Skin Health
    How old are you? 25-34
    What is your gender? Female
    What texture is your hair? Curly
    Rated 5 out of 5 stars
    1 month ago
    Remission

    It’s hard for me to get good photos of the back of my head! Having the shampoo and the MCT oil in addition to the serum made an enormous difference. First photo is Dec 2024 before I started. Second is Jan 2025 after using just the serum and third is a couple days ago with shampoo, serum and MCT. The flare up is receding and the part that is still there is much less intense.

    I am obviously still having a lot of flakes but it has gotten better. Up until a couple weeks ago I could see a LOT of flakes falling when I blew dry my hair. Like from the instant I started blow drying my hair. Now I don’t start shedding until my hair is about 3/4 of the way dry.

    D Profile picture for Dermazen
    Dermazen
    1 month ago

    We're absolutely thrilled to hear about your incredible journey with our products, Lindsay! It's amazing to see you've seen so much progress and that our products have made such an enormous difference in just a few months. We're truly grateful to be part of your journey! 🤗

  • BP
    Bernard P.
    Verified Buyer
    I recommend this product
    Where did you need relief? Scalp
    What did this product help with? Flakes, Itching, Build-Up
    How old are you? 25-34
    What is your gender? Male
    What texture is your hair? Textured
    Rated 5 out of 5 stars
    1 month ago
    Really works!!

    This scalp relief system really works. After dealing with dandruff really bad lately I'm very happy to find something that actually works. Thanks dermazen!

    D Profile picture for Dermazen
    Dermazen
    1 month ago

    We're absolutely thrilled to hear that our products have been so effective for you, Bernard! It's wonderful to know that you've finally found a solution that truly works, especially after struggling with severe dandruff. Nothing makes us happier than knowing we've helped provide real relief for our customers! 🤗

1,000+ Glowing Reviews

Malassezia Safe

Dermatologist Approved

You deserve peaceful skin & peace of mind

CALMER SKIN

Helps reduce flakes, clears away build-up, helps soothe the effects of itching, and calms signs of irritation.

HOLISTIC INGREDIENTS

Skin-friendly antifungal-based ingredients powered by Mother Nature

REVOLUTIONARY APPROACH

Helps to safely disrupt fungal biofilm to weaken the effects of Malassezia while reducing spread of fungus

DERMATOLOGIST REVIEWED & APPROVED

Tested and proven effective by Dr. Maria Bonilla, MD & board-certified dermatologist, as well as other leading doctors and skincare professionals

Get Relief

Enjoy a life free of flaking, itching, and hiding

A revolutionary approach to fungal skin conditions.

The science behind the malassezia fungus is still evolving. Big name brands remain unaware of the Malassezia fungus’ biofilm layer and continue to make products with oils, waxes, and butters that aren’t beneficial for people like us. Because the problem is personal, we stay on the cutting edge of integrating safe, effective and soothing ingredients that help lessen signs of fungus-based irritation.

Our Unique Three-Step Process

1. Disrupt the Biofilm

Malassezia fungus creates a biofilm shield that protects itself from antifungal treatment. We’ve unlocked the secret to help safely diminish or neutralize this barrier.

2. Clear the Fungus

Once the biofilm is removed, our products work together to help reduce signs of fungus easier than ever. We use skin-safe antifungal-based ingredients powered by Mother Nature.

3. Soothe the Skin

Now it’s time to nourish and hydrate your skin without using lipid-based ingredients (like coconut oil, jojoba, etc.) that can help increase the growth of Malassezia fungus.

Designed by humans with moody skin.

We know you because we are you. We know what it’s like to maintain a love/hate relationship with your body, especially your skin. We know how skin has a mind of its own.

Some days it’s happy and calm. Other days are filled with flare ups, flakes, and frustration as you scramble to cover up the irritation. You aren’t obsessed with your looks. You just want calmer skin. You aren’t asking for much.

We have lived your struggles, tried the so-called solutions, and found the secrets to happier, more reliable skin.

Formulated for Peace of Mind

Calming Seborrheic Serum
  • Helps reduce flakes, clears away build-up, helps soothe the effects of itching, and calms signs of irritation.

  • Helps to safely disrupt fungal biofilm to weaken the effects of Malassezia while reducing spread of fungus

  • Works overnight while you sleep and washes out easily

  • Best for scalp but also effective for the face, ears, and chest

Get Relief

Several more formulas on the way

Angled photo of Dermazen's Calming Seborrheic Serum on teal backdrop.

Our story

I was frustrated, confused, and struggling to practice self-love with inflamed skin after 10 years of living with seborrheic dermatitis.

Driven by equal parts hope and desperation, I began crafting my own remedy. Once I discovered the fungus’ biofilm and the importance of oil-free treatment, everything changed.

Within days, my skin was clearer than ever. No bumps. No flakes. No itching. No embarrassment. 

I started making samples for other folks with seborrheic dermatitis. The feedback was remarkable. People started asking for a second bottle. At that point, I realized I had to help more people find relief.

And Dermazen was born. 

Now we focus on educating and empowering folks with seborrheic dermatitis, dandruff, and malassezia imbalance.