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Calming Seborrheic Serum
Calming Seborrheic Serum

“This serum has been a game changer for my dandruff. I’m finally free from the flakes.” - Rachel K., Repeat Customer

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Calming Dandruff Seborrheic Serum

302 reviews

Soothe your scalp overnight. You can stop the itching and flaking right away. This natural formula clears the fungus causing your dandruff and calms your moody scalp.

  • Reduce flakes

  • Nourish Your Scalp

  • Feel Confident

  • Calm Itching

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Dandruff is not dry skin. It’s fungus.

Your scalp is flaking because a fungus (known as malassezia) is bothering your skin. Before you can get rid of your dandruff, you need to clear away the fungus first.

What People Are Saying

“If you’re anything like me, you’ve probably been searching for years for some kind of “magic cure” for your dandruff. While this isn’t some magical permanent cure, it is the next best thing. I’m beyond thrilled with my results, and this product far exceeded my expectations. It’s hard to believe that after 7 years of searching, I have finally been rid of that discomfort. And to Dermazen: Thank you so much for this. You helped with what no other skin product, shampoo, or prescription ever could do for me.” Ashleigh K.

“Listen here y’all! I don’t even know where to begin… About a year ago my scalp started busting and sprouting dandruff. Since then, I have tried a million different products and homemade concoctions to fix it. So it probably took me a month to get the nerve to try this. DO IT! Make the purchase! Add it to your cart right now. I just took my scarf off to investigate and I’m still standing here in disbelief for the last 20 minutes. I had to do this review immediately. Unbelievable! Almost shed a little tear. Enjoy!” Tiffany P.

“This stuff works…plain and simple. No more embarrassing haircuts. No more wearing hats all the time in an effort to cover up. No more leaving a trail of little breadcrumbs everywhere your head lays. After one week of moderate use in conjunction with dandruff shampoo. Boom, gone. I now just use it once or twice a week for maintenance and it’s been staving it off. Super impressed. Great product!!” Nicholas S.

If Dandruff Isn’t Treated, It Gets Worse

When dandruff becomes severe, it evolves into seborrheic (seb • or • ray • ic) dermatitis. It can even spread to the face causing redness and flaking around the nose and eyelashes.

That’s why our most effective dandruff formula is called the Calming Seborrheic Serum.

Two Secrets to Stopping Dandruff

Most dandruff treatments fail because they don’t neutralize the biofilm protecting the fungus and they contain oils that feed the fungus.

Secret #1

Disrupt the Biofilm

The fungus causing dandruff has a biofilm “shield” that blocks antifungal treatments.

Dermazen dissolves this biofilm naturally so the fungus can be removed.

Secret #2

Starve the Fungus

The malassezia fungus feeds on oils like coconut oil, shea butter, jojoba, etc.

If you want lasting relief, you need to soothe your skin without fungus-feeding oils.

Trusted By Experts

“I have been recommending the Calming Seborrheic Serum to my patients with seborrheic dermatitis and psoriasis and they have seen significant improvement in their skin.”

- Dr. Maria Bonilla

Why Other Dandruff Treatments Fail

Most dandruff treatments fail because they don’t neutralize the biofilm protecting the fungus and they contain oils that feed the fungus.

Other Treatment


Doesn't treat the biofilm

Safely disrupts biofilm

Feeds the fungus

Formulated without oils

Harmful chemicals

Potent natural ingredients

Other Treatment

Doesn't treat the biofilm

Feeds the fungus

Harmful chemicals


Safely disrupts biofilm

Formulated without oils

Potent natural ingredients

What’s Inside

200x Concentrated Aloe

Soothe your irritated scalp and calm inflamed skin


Naturally disrupt the biofilm layer to weaken the fungus

Grapefruit Seed Extract

Eliminate fungus and boost antioxidants

Tea Tree Essential Oil

Calm inflammation and eliminate fungus

See All Ingredients

How to Get Rid of Flakes & Itching

  • 1

    Start by applying a generous amount of the serum to your scalp.

  • 2

    Massage in the formula as you thank your body for all its hard work.

  • 3

    Allow the serum to absorb fully overnight.

  • 4

    Wash it out in the morning with your shampoo of choice.

  • 5

    Finally, enjoy a life free of itching and flaking.

Customer Reviews
4.6 Based on 333 Reviews
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Pretty Good

I apply this when my scalp is itchy or shedding and it calms it down. However, be ready to take a shower if you need to style your hair as it creates a wet gel look.

Rachel B.
United States

The best stuff ever

I started using the moisturizer and calming serum and within days my skin smoothed out. I have always had acne prone, sensitive skin. I get cysts and clogged poors, and my skin LOVESSSS this stuff. I am so happy I found this. Incredible natural ingredients too!? It’s a win win win for me.

United States United States

Healing energy

A skin calming addition to your regiment

Patrick O.
United States United States

Good product

Kind of burns at first. But I think it helps

Ofek K.
United States United States


This worked really well for me. Saw results almost immediately

United States United States


I have battled seborrheic dermatitis my entire life. I've used prescription topical treatment and tried other more natural treatments on my own. Nothing has worked for me like Dermazen, to the point I'm am about to invest in the entire set. I have zero redness, zero flakes and peeling within a week after using, which means less itching as well. Please stay in business forever! You have a customer for life!

Shelley H.
United States United States

Seems helpful but process is difficult

I think it is helping, but washing hair/applying/letting it sit/washing hair again is a tough thing for me to build into my day. I have started braiding my hair after using it to manage because it is tacky when you leave it in and that is tricky with long hair. However, it does seem to be working. Overall my scalp is much more comfortable. But it does require regular use it seems. The price is hefty for how much you get which is unfortunate. So, overall, it seems good but working it into your routine can be tough and the price is high.

Kalie H.
United States United States

Bump cure!

Had an issue with tiny raised tiny pore bumps and this completely smoothed out my skin. One star off because it is very liquidy so I would call it a toner, not a serum. Ordering another one right now!

Sophie T.
United States United States

Great experience

Works and is a game changer

Shaye N.
United States United States
Dermazen Calming Seborrheic Serum Review


I’ve tried numerous products in my lifetime, trying to alleviate my scalp issues. Nothing has worked. My expectations were low, but this exceeded them. The serum has greatly reduced my seborrheic dermatitis; I’m truly impressed and will continue to use.

k t.
United States United States


My scalp feels a lot better while using this product. I love it!!

Mary L.
United States United States

Helps control seborrheic flare ups

Have been using twice daily for about a month and notice fewer flareups of facial seborrheic dermatitis. Would purchase again.

Tyler W.
United States United States